Allen脑图谱中小鼠大脑低相关空间基因表达模式的聚类

Paolo Rosati, C. Lupascu, D. Tegolo
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引用次数: 1

摘要

本文将聚类技术应用于矢状和冠状投影之间基因组相关性较低的空间基因表达模式。这里分析的数据托管在一个名为ABA (Allen Brain Atlas)的可用公共数据库上。结果与Bohland等人在互补数据集(高相关值)上获得的结果进行了比较。我们证明,通过分析简化的数据集,从而减少计算负担,我们在突出不同的神经解剖区域时获得相同的准确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clustering of low-correlated spatial gene expression patterns in the mouse brain in the Allen Brain Atlas
In this paper, clustering techniques are applied to spatial gene expression patterns with a low genomic correlation between the sagittal and coronal projections. The data analysed here are hosted on an available public DB named ABA (Allen Brain Atlas). The results are compared to those obtained by Bohland et al. on the complementary dataset (high correlation values). We prove that, by analysing a reduced dataset,hence reducing the computational burden, we get the same accuracy in highlighting different neuroanatomical region.
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