对揭示糖尿病足早期风险的特异性刺激试验的多模态反应的评估

Sergej Sosunkevič, Andrius Rapalis, Mindaugas Marozas, Vilma Pluščiauskaitė, Lina Surgautė, A. Lukoševičius
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引用次数: 0

摘要

2型糖尿病在21世纪成为一种流行病。对许多人来说,糖尿病长期无症状,并导致严重的心血管和神经系统疾病,如糖尿病足。所有病理和心血管的改变和损害都能被识别;然而,所有的方法都是主观的,不能提供信息。由于这些原因,在早期阶段糖尿病足评估的新方法是必要的。本研究的目的是详细阐述该方法的试点版本,该方法允许验证特定刺激测试和分析生理信号的同步多模态时间依赖性可以揭示糖尿病足的早期风险并识别损伤类型的假设。10名参与者参加了这项研究。实验包括三种不同的测试:缓慢呼吸、寒冷和闭塞。对来自所有同步源的数据流进行处理并用于计算次要参数:心率变异性、脉搏到达时间、灌注因子和足部温度。两组的初步结果表明,特定的刺激试验引起了显著不同的变化。初步结论:该方法可用于早期糖尿病足风险的筛查,并可能用于损伤类型的识别。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Multimodal Reactions on Specific Stimulation Tests for Revealing Early Risk of Diabetic Foot
Diabetes mellitus type 2 became an epidemic in the 21st century. For many people diabetes remains asymptomatic for a long-term and leads to severe cardiovascular and neurological disorders such as diabetic foot. All pathological and cardiovascular changes and damages can be identified; however, all methods are subjective and noninformative. For these reason, a novel methodology for diabetic foot assessment in early stages is necessary. The aim of this study is to elaborate a pilot version of method which allows to verify the hypothesis that specific stimulation tests and analysis of synchronous multimodal time dependences of physiological signals can reveal the early risk of diabetic foot and identify the type of damage. Ten participants were enrolled in the study. The experiment consists of three different tests: slow breathing, cold, and occlusion. Data stream from all synchronous sources was processed and used to calculate secondary parameters: heart rate variability, pulse arrival time, perfusion factor, and temperature of foot regions. The preliminary results of both groups have shown that specific stimulation tests induced significantly different changes. Preliminary conclusion can be made that proposed method be used for screening of early diabetic foot risks and probably for identification of type of damage.
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