肿瘤检测与介电剖面估计的数据库技术

Priyansha Kaurav, S. Koul, A. Basu
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引用次数: 0

摘要

生物医学成像技术有助于检测肿瘤并找到肿瘤细胞在体内的确切位置。但是这些技术非常耗时,所需的设置也非常庞大。他们还需要组织介电特性的先验信息,以给出准确的成像结果。从简单的测量和模拟过程中可以提取有关肿瘤和介电剖面的相当有用的信息。早先,利用介电探针和波导夹具技术提供了生物组织的介电剖面。这些方法提供了合理的估计,但所使用的设置仅限于一小部分组织,不能适应整个身体部位。本文提出了一种利用自由空间传输法和数据库方法分析乳腺组织中有无肿瘤细胞介电分布的新方法。测量装置用于在自由空间中获得传输参数,使被测组织保持在发射器和接收器天线之间。利用德拜模型建立了模拟传输参数数据库,保留了组织类型的所有变化集。然后将测量的传输参数数据与数据库进行匹配,得到复介电常数。该技术通过模拟真实的乳房幻影和小鼠肿瘤细胞的结果进行了验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Database Technique for Tumor Detection and Dielectric Profile Estimation
Bio-medical imaging techniques help in detection the tumor and finding the exact location of tumor cells inside the body. But these techniques are time consuming and the setup required is bulky. They also require a prior information about dielectric properties of tissue to give accurate imaging results. Quite useful bits of information regarding tumor and dielectric profile can be extracted from simple measurement and simulation procedure. Earlier, dielectric profile of biological tissue was provided using dielectric probe and waveguide fixture techniques. These methods provided reasonable estimates, but the setup which was used is limited to small portion of tissues and were not able to accommodate body part as a whole. In this paper, a new technique is devised to analyze the dielectric profile of breast tissues with and without tumor cells using free space transmission method and database approach. The measurement setup is used to obtained the transmission parameters in free space keeping the tissue under test in between the transmitter and receiver antenna. Database of simulated transmission parameter is created keeping all sets of variations in tissue types using Debye model. The complex permittivity is then arrived at by matching the measured transmission parameter data with the database. This technique was validated using simulated realistic breast phantoms and tested with results from mouse tumor cells.
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