肠组织性癌症:患失联和营养不良75 *

G. Kolb
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引用次数: 0

摘要

几乎三分之二的75岁及以上、计划进行结直肠癌手术的患者营养不良。尽管有证据表明围手术期营养管理可以改善患者的预后,但国际指南在目前的实践中仍然没有得到充分的应用。在这项对五家外科医院进行的楔形聚类随机研究中,我们纳入了147名年龄在70岁及以上的患者,他们在2013年10月至2016年12月期间计划进行腹部结直肠癌手术。在干预条件下,由一名老年病专家和一名营养师组成的外展小组访问了外科病房的患者和工作人员,以协助正确应用指南。干预组39.2%的患者认为评估、诊断和处方(根据营养状况)是适当的,并严格符合指南,而对照组只有1.4% (p = 0.0002)。围手术期口服营养补充剂处方明显改善(41.9% vs. 4.1%;P < 0.0001)。然而,对手术并发症或不良事件的干预没有好处。减少住院时间可能带来的好处需要在进一步的研究中得到证实。本研究强调了在老年结直肠癌患者围手术期营养管理实践中实施质量改善干预的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Kolorektales Karzinom: Fehl- und Mangelernährung bei Patienten 75+
Almost two in three patients who are aged 75 years and older and scheduled for surgery for colorectal cancer (CRC) are undernourished. Despite evidence that perioperative nutritional management can improve patients outcomes, international guidelines are still insufficiently applied in current practice. In this stepped-wedge cluster-randomized study of five surgical hospitals, we included 147 patients aged 70 years or older with scheduled abdominal surgery for CRC between October 2013 and December 2016. In the intervention condition, an outreach team comprising a geriatrician and a dietician visited patients and staff in surgical wards to assist with the correct application of guidelines. Evaluation, diagnosis, and prescription (according to nutritional status) were considered appropriate and strictly consistent with guidelines in 39.2% of patients in the intervention group compared to only 1.4% in the control group (p = 0.0002). Prescription of oral nutritional supplements during the perioperative period was significantly improved (41.9% vs. 4.1%; p < 0.0001). However, there were no benefits of the intervention on surgical complications or adverse events. A possible benefit of hospital stay reduction will need to be confirmed in further studies. This study highlights the importance of the implementation of quality improvement interventions into current practice for the perioperative nutritional management of older patients with CRC.
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