蛋白质序列的基序检测

6th International Symposium on String Processing and Information Retrieval. 5th International Workshop on Groupware (Cat. No.PR00268) Pub Date : 1999-09-21 DOI:10.1109/SPIRE.1999.796579

Yuan Gao, K. Mathee, G. Narasimhan, Xuning Wang

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引用次数: 15

摘要

我们利用数据挖掘和知识发现的方法设计了一种检测蛋白质序列中基序的算法。基于这种方法，我们实现了一个名为“GYM”的程序。使用Helix-Turn-Helix Motif作为模型系统来测试我们的程序。该程序还扩展到检测同域基序。对这两个基序的检测结果与现有程序比较良好。此外，GYM程序提供了许多关于给定蛋白质序列的有用信息。

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Motif detection in protein sequences

We use methods from data mining and knowledge discovery to design an algorithm for detecting motifs in protein sequences. Based on this approach, we have implemented a program called "GYM". The Helix-Turn-Helix Motif was used as a model system on which to test our program. The program was also extended to detect Homeodomain motifs. The detection results for the two motifs compare favorably with existing programs. In addition, the GYM program provides a lot of useful information about a given protein sequence.

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来源期刊

6th International Symposium on String Processing and Information Retrieval. 5th International Workshop on Groupware (Cat. No.PR00268)

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