芳烃受体(AhR)在微生物感染免疫应答中的作用

Antimicrobial Immune Response [Working Title] Pub Date : 2021-03-01 DOI:10.5772/INTECHOPEN.96526

Lixing Huang, Rongchao He, Youyu Zhang, Q. Yan

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摘要

芳烃受体(Aryl hydrocarbon receptor, AhR)是一种重要的核受体，可调节细胞对环境胁迫的反应。它因其在毒理学中的关键功能而闻名，但目前被认为是疾病的重要调节剂，对免疫、抗菌和炎症反应具有特定的调节作用。本章讨论AhR在对抗微生物感染的免疫反应中的作用和机制。

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The Role of the Aryl Hydrocarbon Receptor (AhR) in the Immune Response against Microbial Infections

Aryl hydrocarbon receptor (AhR), an important nuclear receptor, regulates the cellular response to environmental stressors. It is well known for its critical functions in toxicology, but is currently considered an essential regulator of diseases, with specific modulatory effects on immune, antimicrobial and inflammatory responses. The present chapter discusses AhR’s function and mechanism in the immune response against microbial infections.

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Antimicrobial Immune Response [Working Title]

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