Comparison of Vomiting Induced by Medetomidine Xylazine in Cats.

The comparative study of vomiting induced by medetomidine or xylazine was performed in cats. Medetomidine (80ƒÊg/kg) or xylazine (2mg/kg) was administered in tramuscularly in cats. The vomiting was induced in 20.0% of cats in medetomidine group and in 70.0% of those in xylazine group. One vomiting reaction was the most common frequency in both groups, however the mean frequency of vomiting was 2.1 in medetomidine group and 2.0 in xylazine group, respectively. The vomiting was commonly induced during 2-3 min after the administration of medetomidine or xylazine. Sedation was induced (laying down) in average at 3 min 15 sec in medetomidine group and 6 min 51 sec in xylazine group, respectively. The results suggest that at these doses, medetomidine is more effective than xylazine to reduce the accident induced by vomiting and owner's anxiety during the induction phase of sedation.