COVID-19大流行中的毛霉菌病:涉及印度奥兰加巴德地区三级医院的研究

P. Muley, H. Gupta, Abha Gupta
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摘要

导读:在2019冠状病毒病大流行期间,观察到印度毛霉菌病患者突然增加。在奥兰加巴德的三级保健医院进行了一项集体研究。材料和方法:与奥兰加巴德市政公司(AMC)、oralcare.co.in和奥兰加巴德SNDH医院合作,在奥兰加巴德(马哈拉施特拉邦)进行了一项回顾性描述性研究。AMC从奥兰加巴德的3家主要三级医院收集了数据,这些医院于2021年5月至2021年7月对毛霉病进行了治疗。本研究纳入了AMC接收的135例毛霉菌病患者的资料。包括患者的人口统计资料、医疗和临床病史、COVID - 19病史、COVID - 19治疗、毛霉病类型、毛霉病的治疗和结果。结果:本组毛霉病患者中男性占74.7%。77.4%的毛霉病患者年龄在50岁以上。研究发现,约67%的毛霉菌病患者以糖尿病为最常见的危险因素。约87.4%的患者有COVID-19病史。研究人群中大多数患者被诊断为鼻-上颌-眶型毛霉菌病,占39%,其次是鼻-脑型,占25%。仅有1%的患者表现为鼻鼻眶型毛霉菌病,30%的患者不属于任何类型。研究人群中所有患者均接受两性霉素B和手术治疗。毛霉病治疗后出院率约为84.4%。15.6%患者在治疗中或治疗后死亡。结论:毛霉菌病以50岁以上男性多见,新冠肺炎感染和糖尿病是毛霉菌病的常见危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mucormycosis in COVID-19 Pandemic: Study Involving Tertiary Hospitals in Aurangabad District, India
Introduction: An abrupt increase in the mucormycosis patients in india during the COVID 19 pandemic was observed. A collective study was conducted in tertiary care hospitals in Aurangabad. Materials and Methods: A retrospective descriptive study was conducted in Aurangabad (Maharashtra), in association with the Aurangabad Municipal Corporation (AMC), oralcare.co.in and SNDH Hospital, Aurangabad. Data was collected by AMC from 3 major tertiary hospitals present in Aurangabad where treatment of Mucormycosis was done from May 2021 to July 2021. The data of total 135 patients with Mucormycosis was received by the AMC were included in the study. It included demographics of the patients, medical and clinical history, history of COVID 19, treatment of COVID 19, type of Mucormycosis, treatment and outcomes of Mucormycosis. Results: In the present study, 74.7% of Mucormycosis patients were males. 77.4% of Mucormycosis patients were above 50 years of age. It was seen that about 67% of patients with Mucormycosis had diabetes mellitus as the most common risk factor. About 87.4% of patients had a history of COVID-19. Majority of the patients in the study population were diagnosed with the rhino-maxillary-orbital type of Mucormycosis which is 39%, followed by the rhino-cerebral type-25%. Only 1% patients showed rhiono-nasal -orbital type of Mucormycosis. 30% patients were not categorised into any type. All the patients in the study population received amphotericin B and surgical treatment. About 84.4% patients were discharged after the Mucormycosis treatment. 15.6% patients died during or after the treatment. Conclusion: Mucormycosis was predominantly seen in male above the age of 50 years, COVID-19 infection and diabetes mellitus was common risk factor for Mucormycosis.
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