从枇杷果中提取的固定油可以防止由生物质引起的室内空气污染引起的呼吸系统组织和功能的改变

Allison Matias de Sousa, F. L. Gondim, Gilvan Ribeiro dos Santos, Marcelle Ferreira Moura, Ruth Mesquita Ferreira, D. S. Serra, A. Pimenta, M. L. Oliveira, F. S. Cavalcante
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引用次数: 0

摘要

生物质残渣的再利用可以有不同的方式,例如通过压实绿色椰子壳获得颗粒。尽管有这些优点,但研究表明生物质燃烧是家庭空气污染的主要来源。室内污染还与被认为有风险的群体(如哮喘患者)的严重后果有关。因此,人们正在通过具有抗炎特性的天然产品寻找替代和低成本的治疗方法,例如Caryocar coriaceum (CC)的固定油。在本研究中,我们评估了口服CC摄入对慢性暴露于椰子壳颗粒(CSP)燃烧产生的烟雾模型小鼠呼吸系统的影响,并对ova诱导的哮喘模型小鼠进行了研究。我们对暴露室的气体成分进行了分析,并分析了呼吸系统的不同方面。CC可预防炎症细胞浸润和肺泡塌陷。此外,它能够避免气道阻力,组织阻力,弹性,顺应性和吸气量的变化。我们的研究结果证明了长期暴露于室内污染的影响,并表明饮食摄入CC可能是预防呼吸系统疾病的一种策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FIXED OIL DERIVED FROM Caryocar coriaceum (PEQUI FRUIT) PREVENTS TISSUE AND FUNCTIONAL ALTERATIONS IN THE RESPIRATORY SYSTEM INDUCED HOUSEHOLD AIR POLLUTION ORIGINATING FROM BIOMASS
The reuse of biomass residue can be in different ways, such as pellets obtained through the compaction of green coconut shell. Despite the advantages, studies relate the burning of biomass as the main source of household air pollution. Indoor pollution is also correlated with serious consequences for groups considered at risk, such as asthmatics. As a result, the population is looking for alternative and low-cost treatments through natural products with anti-inflammatory characteristics, such as the fixed oil of Caryocar coriaceum (CC). In the present study, we evaluated the effects of oral CC ingestion on the respiratory system of mice submitted to a model of chronic exposure to smoke from the combustion of coconut shell pellets (CSP) and submitted to the OVA-induced asthma model. We performed analysis of the gaseous composition in the exposure chamber and analyzes of different aspects of the respiratory system. CC could prevent inflammatory cell infiltration and alveolar collapse. Furthermore, it was able to avoid changes in the airway resistance, tissue resistance, elastance, compliance and inspiratory capacity. Our findings demonstrate the effects of long-term exposure to indoor pollution and suggest that dietary intake of CC may be a strategy to prevent respiratory diseases.
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