Cellular Microbiology: Indispensable Tool to Dissect Host Pathogen Interaction

The threat of the spread of new or old infectious diseases are always a concern for human civilization. The emergence of coronavirus disease (COVID-19) and its dissemination around the world has demonstrated the risk to human health and the economy. So, it is essential to study a complete understanding of the host-pathogen interaction for the development of the disease. The field of cellular microbiology can help in the identification and characterization of different virulence factors produced by pathogens during each step of the infection process by combining techniques and approaches of classic cell biology and microbiology. Currently, the dynamic interaction of the host-pathogen relationship has been enhanced due to the cell culture, in vivo methods, in addition to microbial genomics, bioinformatics techniques, and in silico prediction methods to understand these diseases for the development of prevention methods, diagnosis and treatment worldwide.