A. Alves, G. Kizi, A. R. Barata, P. Mascarenhas, I. Ventura
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引用次数: 0
摘要
癌症治疗的目标是对抗和/或控制癌症。本研究的目的是回顾和荟萃分析儿科肿瘤化疗期间主要口腔并发症的发生率。检索结果来源于B-on、Web of Science、Scopus、Cochrane Library和PubMed数据库。在1032篇可能相关的文章中，13篇纳入本综述。龋齿、牙龈炎、溃疡、粘膜炎和念珠菌病的总发病率分别为67.8%、55.6%、44.2%、41.6%和29.5%。在化疗期间，儿科癌症患者出现较高的龋齿和牙龈炎发生率。发病率荟萃分析显示高异质性。应该做更多的研究来减少不确定性。
Oral Complications of Chemotherapy on Paediatric Patients with Cancer: A Systematic Review and Meta-Analysis
The goal of cancer treatment is to fight and/or control cancer. The aim of this study was to review and meta-analyse the incidence of main oral complications in paediatric oncology during chemotherapy. The search results were obtained from B-on, Web of Science, Scopus, Cochrane Library and PubMed databases. Of 1032 articles potentially relevant, 13 were included in this review. The overall incidence of caries, gingivitis, ulcers, mucositis, and candidiasis was 67.8%, 55.6%, 44.2%, 41.6%, and, 29.5%, respectively. During chemotherapy, paediatric patients with cancer present higher incidence of caries and gingivitis. Incidence rate meta-analysis show high heterogeneity. More studies should be done to reduce uncertainty.
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