壳聚糖包被pla -胶原中空纤维用于血管移植工程

2019 International Biomedical Instrumentation and Technology Conference (IBITeC) Pub Date : 2019-10-01 DOI:10.1109/IBITeC46597.2019.9091680

Dita Ayu Mayasari, P. Widiyanti, Djonny Izak Rudyardjo

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引用次数: 1

摘要

合成材料是血管移植工程中常用的材料。PLLA是一种可生物降解的聚合物，适合于这种应用。本研究在表面添加壳聚糖制备了一种基于血管移植的pla -胶原。本研究的目的是评价壳聚糖包被pla -胶原中空纤维的力学性能。采用拉伸空气技术，利用喷丝装置制备pla -胶原蛋白中空纤维。采用亲笔签名法测定了壳聚糖包被pla -胶原中空纤维的机械强度。结果表明，壳聚糖的加入降低了pla -胶原中空纤维的极限拉伸强度。

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Chitosan-Coated PLLA-Collagen Hollow Fiber for Vascular Graft Engineering

Synthetic materials is commonly used on vascular graft engineering. PLLA which a biodegradable polymers is suitable for this application. In this study, a vascular graft based PLLA-collagen was made with added chitosan on its surface. The aim of this research is to evaluate the mechanical properties of chitosan-coated PLLA-collagen hollow fiber. PLLA-collagen hollow fiber is made from stretch air technique using spinneret apparatus. The mechanical strength of chitosan-coated PLLA-collagen hollow fiber was measured using autograph. The result showed that the addition of chitosan decrease the ultimate tensile strength of PLLA-collagen hollow fiber.

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2019 International Biomedical Instrumentation and Technology Conference (IBITeC)

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