利用层析成像图像和角膜的生物力学参数建立角膜的三维几何结构

Eduardo Pinos, Roberto Coronel, M. Cordero
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引用次数: 0

摘要

目前,有各种影响角膜结构的疾病,如果不及时治疗,会造成角膜结构的损伤,从而影响人们的正确视力,在这种情况下,患者会去看眼科医生,由眼科医生通过临床研究确定角膜结构的病理和损伤程度,在很多情况下,需要手术来纠正这种损伤,然而,有些情况下,手术后角膜的结构会进一步受损,进一步影响视力。为了避免手术后的损伤,通过分析角膜生物力学及其特性,以及对角膜组织的形态学分析,观察这些疾病所产生的物理变化,寻找更有效的方法来确定患者是否需要手术。为了研究角膜组织的物理结构和作用在角膜组织上的力,本文构建了角膜表面,为此,分析了不同类型的弹性、超弹性和粘弹性模拟材料,其特征类似于角膜组织在张力和变形条件下的柔性行为,并从角膜断层扫描图像中获得了三维角膜几何形状。从眼科检查中提取。因此,将角膜的三维几何形状与弹性、泊松比和分配给模拟材料的密度的特性统一起来,就得到了与自然角膜组织相似的角膜模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Three-dimensional construction of the corneal geometry from tomographic images and biomechanical parameters of the cornea
Currently, there are various diseases that affect the corneal structure, when not treated in a timely manner can cause damage to the corneal structure, which affects the correct vision of people, in these cases the patient goes to the ophthalmologist, who through clinical studies determines the pathology and the degree of impairment of the corneal structure, in many cases surgery is necessary to correct this damage, however, there are cases in which after surgery the cornea suffers further damage to its structure, further affecting the visual acuity.To avoid damage after surgery, more effective methods are searched to determine whether the patient requires surgery or not, by analyzing the corneal biomechanics and its properties, in addition, the morphological analysis of the corneal tissue that allows observing the physical changes produced by these diseases. With the purpose of studying the physical structure and the forces applied on the corneal tissue, this article presents a construction of the corneal surface, for this, different types of elastic, hyperelastic and visco-elastic materials for simulation have been analyzed, whose characteristics resemble the flexible behavior of the corneal tissue in conditions of tension and deformation, in addition, a three-dimensional corneal geometry has been obtained from images of corneal tomographies, which were extracted from ophthalmologic examinations. Consequently, the unification of the three-dimensional geometry of the cornea with the properties of elasticity, Poisson's ratio and density assigned to a simulation material, results in a corneal model that resembles the natural corneal tissue.
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