{"title":"基于多目标进化算法的可解释模糊模型微阵列基因表达数据分析","authors":"Zhenyu Wang, V. Palade","doi":"10.1109/BIBM.2010.5706582","DOIUrl":null,"url":null,"abstract":"We believe the great interpretability of fuzzy models allow fuzzy-based methods to play a very important role in Microarray gene expression data analysis, but the advantages offered by fuzzy-based techniques in this application have not yet been fully explored in the literature. In this paper, we construct Multi-Objective Evolutionary Algorithms based Interpretable Fuzzy (MOEAIF) models for microarray gene expression data analysis. Our novel fuzzy models can significantly decrease the model complexity, and automatically balance the accuracy and interpretability of the models. The experimental studies have shown that relatively simple and small fuzzy rule bases, with satisfactory classification performance, have been successful found for challenging microarray gene expression datasets.","PeriodicalId":275098,"journal":{"name":"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Multi-objective evolutionary algorithms based Interpretable Fuzzy models for microarray gene expression data analysis\",\"authors\":\"Zhenyu Wang, V. Palade\",\"doi\":\"10.1109/BIBM.2010.5706582\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We believe the great interpretability of fuzzy models allow fuzzy-based methods to play a very important role in Microarray gene expression data analysis, but the advantages offered by fuzzy-based techniques in this application have not yet been fully explored in the literature. In this paper, we construct Multi-Objective Evolutionary Algorithms based Interpretable Fuzzy (MOEAIF) models for microarray gene expression data analysis. Our novel fuzzy models can significantly decrease the model complexity, and automatically balance the accuracy and interpretability of the models. The experimental studies have shown that relatively simple and small fuzzy rule bases, with satisfactory classification performance, have been successful found for challenging microarray gene expression datasets.\",\"PeriodicalId\":275098,\"journal\":{\"name\":\"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/BIBM.2010.5706582\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BIBM.2010.5706582","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Multi-objective evolutionary algorithms based Interpretable Fuzzy models for microarray gene expression data analysis
We believe the great interpretability of fuzzy models allow fuzzy-based methods to play a very important role in Microarray gene expression data analysis, but the advantages offered by fuzzy-based techniques in this application have not yet been fully explored in the literature. In this paper, we construct Multi-Objective Evolutionary Algorithms based Interpretable Fuzzy (MOEAIF) models for microarray gene expression data analysis. Our novel fuzzy models can significantly decrease the model complexity, and automatically balance the accuracy and interpretability of the models. The experimental studies have shown that relatively simple and small fuzzy rule bases, with satisfactory classification performance, have been successful found for challenging microarray gene expression datasets.