利多卡因与地塞米松减轻全身麻醉后喉咙痛的比较研究

Mohammed Mohammed, Ali El Said Rashad
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引用次数: 0

摘要

背景术后喉咙痛(POST)是气管插管后患者常见的症状。本研究比较静脉注射利多卡因与地塞米松预防此类问题的疗效。患者和方法将394例患者随机分为两组:D组197例静脉注射地塞米松(8 mg), L组197例静脉注射利多卡因(1.5 mg/kg)。对POST的发病率和危险因素进行了评估。结果L组出现喉咙痛115例(58.4%),而另一组出现喉咙痛82例(41.6%)。D组患者咽喉痛感明显减轻(P<0.001)。Logistic回归分析显示,吸盘上有血是插管后发生咽喉痛的重要危险因素。结论静脉给药地塞米松比利多卡因更有可能降低POST的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study
Background Postoperative sore throat (POST) is commonly reported by patients after endotracheal intubation. This study was conducted to compare the efficacy of intravenous lidocaine and dexamethasone in the prevention of such problem. Patients and methods We included a total of 394 cases who were randomly divided using the closed-envelope method into two groups: group D that included 197 cases who received intravenous dexamethasone (8 mg), and group L that included the remaining 197 cases who received intravenous lidocaine (1.5 mg/kg). Both the incidence and risk factors for POST were assessed. Results Sore throat was reported by 115 (58.4%) cases in group L, whereas it was reported by 82 (41.6%) cases of cases in the other group. There was a marked reduction of sore-throat sensation in group D (P<0.001). Logistic regression revealed that the presence of blood on suction was a significant risk factor for developing sore throat after intubation. Conclusion Intravenous administration of dexamethasone appears to be more promising than lidocaine in decreasing the incidence of POST.
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