利用遗传算法建模病毒进化和流行病模拟

Jun-Seok Paek, Hagun Yoo, Dain Kyung
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引用次数: 0

摘要

本研究引入遗传算法模拟病毒突变,了解病毒性状和人体免疫的变化。在模拟中,当感染人数超过5%时,人员随机移动,并实施社会距离措施。病毒由两个特征来定义:人类之间的感染率和病毒攻击,分别用字符串和浮点基因表示。疾病的进展是通过基于病毒攻击和人类恢复速度之间竞争的“生命系统”来计算的。根据遗传相似性将病毒分为亚种。通过对各物种性状变化的分析,认为感染率的增加和体内病毒攻击的减少是有利于病毒存活的变异。将模拟结果与瑞典每日新增确诊病例进行比较,验证了模拟的准确性。与现有的传播模型相比,该模拟在突变和免疫的实现方面更加真实和适应性强。预计,通过分析检疫政策的效果,可以大幅减少传染病造成的损失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modeling Viral Evolution and Epidemic Simulation Using Genetic Algorithms
In this study, Genetic Algorithm was introduced to simulate virus mutation and to understand the changes in viral traits and human immunity. In the simulation, humans move randomly and social distancing measures are implemented when the number of infected humans exceeds 5%. The virus is defined by two traits: the infection rate between humans and the virus attack, represented by strings and floating-point genes, respectively. The progression of the disease is calculated through the “life system” based on the competition between the virus attack and the human recovery rate. The viruses were classified into subspecies based on genetic similarity. Through analysis of the changes in traits per species, it was concluded that an increase in infection rate and a decrease in virus attack within the body were favorable variations for the survival of the virus. Simulation results were compared with the daily new confirmed COVID-19 cases in Sweden, demonstrating accuracy of the simulation. This simulation is more realistic and adaptable in terms of the implementation of mutations and immunity compared to existing spread models. It is expected that by analyzing the effectiveness of quarantine policies, the damage caused by infectious diseases could be reduced drastically.
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