A bridge between diabetes and periodontitis

Periodontitis is a chronic inflammatory multifactorial disease that affects the supporting structures of teeth, affects the quality of life, and causes the destruction of multiple organs, on the other hand, diabetes is a group of metabolic diseases characterized by increased levels of glucose in the blood (hyperglycemia) resulting from defects in insulin secretion, insulin action, or both. Studies have shown that periodontitis patients have three times more risk of getting diabetes and evidence shows that cytokine, neutrophil, and inflammatory activity relate to both diabetes and periodontitis. This review article intends to cover the vast dilemmas that exist in relation to the double-edged sword; diabetes and periodontitis.