经颈静脉肝内门静脉大循环短路术(TIPS)对50例难治性腹水的治疗成绩

秀典 金沢, 義之 楢原, 健二 福田, 千紗 近藤, 滉智 張本, 洋子 松下, 秀子 城所, 玲樹 片倉, 正則 厚川, 保彦 滝, 祐 木村, 祐二 長田, 雄久 中塚, 長逸 坂本
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引用次数: 1

摘要

在这项前瞻性队列研究中,我们评估了50例Child-Pugh评分为9.8分的难治性腹水患者使用经颈静脉肝内门系统分流术(TIPS)。平均随访时间为592天。1年后腹水改善96%,2年后腹水改善93%。1年、2年和5年的累计生存率分别为71%、52%和18%。TIPS治疗后Child-Pugh评分和表现状态评分均有显著提高。由于分流管狭窄,36例患者在随访期间需要进行分流管翻修。肝性脑病经医学控制的有26例。我们的研究结果表明,虽然可能需要分流修正,TIPS可以控制难治性腹水在大多数生存病例和改善生活质量。然而,我们的tips治疗的难治性腹水患者的5年生存率仍然很低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
経頸静脈的肝内門脈大循環短絡術(TIPS)による難治性腹水50例の治療成績
: In this prospective cohort study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 50 patients with refractory ascites and a Child-Pugh score of 9.8. The mean duration of follow-up was 592 days. Ascites improved in 96% at 1 year and in 93% at 2 years. The cumulative survival rate was 71%, 52% and 18% at 1, 2 and 5 years. The Child-Pugh score and the performance status score improved significantly after TIPS. Thirty six patients required shunt revision during follow-up, due to shunt stenosis. Hepatic encephalopathy which was able to be controlled medically occurred in 26 patients. Our results suggest that although shunt revision may be needed, TIPS can control refractory ascites in most survival cases and improve QOL. However, the 5-year survival rate is still low in our TIPS-treated patients with refractory ascites.
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