基于知识图谱的智能远程医疗药物副作用数据表示与全谱推理

Saravanan Jayaraman, Lixin Tao, Keke Gai, Ning Jiang
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引用次数: 7

摘要

药物副作用数据包含了组份药物和复方药物的副作用和避免冲突的重要约束。这些对于检查处方以避免并发症至关重要。目前XML中的药物数据副作用表示没有一个合适的知识表示机制来清晰地指定药物组件和药物之间的各种依赖关系。因此,医生和护理人员经常依靠人工解释来检查处方,这可能容易出错。最近引入的基于Web本体语言(OWL)的医疗药物副作用数据表示方法仍然存在OWL限制固有的一些缺点,例如使用“is-a”关系和使用基于对象属性的变通方法,失去了领域专家所期望的表示知识的清晰度和动态关系构建。使用知识图(KG)和增强的PaceJena构建的药物副作用表示和推理(D-SERI)模型表明,所提出的模型允许医生和护理人员获得有关副作用的动态信息,避免由人工解释引起的代价高昂的错误。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Drug Side Effects Data Representation and Full Spectrum Inferencing Using Knowledge Graphs in Intelligent Telehealth
Drug side effects data contains important constraints about side-effects and conflict avoidance of component and compound drug. These are critically important in checking out prescriptions to avoid complications. Current drug data side effect representations in XML does not have a proper knowledge representation mechanism to clearly specify all kinds of dependencies among the drug components and drugs. Therefore Doctors and caregivers often rely on human interpretation to check prescriptions which can be error-prone. The recently introduced Web Ontology Language (OWL) based approach for medical drug side effects data representation still suffers from several shortcomings inherent to the OWL restrictions like using "is-a" relationship and usage of object property based workarounds losing the clarity and dynamic relationship building expected by domain experts to represent knowledge. The proposed model Drug-Side Effects Representation And Inferencing (D-SERI) built using Knowledge Graph (KG) and enhanced PaceJena shows that the proposed model allowsthe doctors and caregivers to derive dynamic information about side effects avoiding costly errors caused by human interpretation.
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