When Successive Viral Mutations Prevent Definitive Treatment of COVID-19

SARS-CoV-2 In this at new mutations in COVID-19 as well as the adverse effects of the virus on the and gastrointestinal tract. The discovery of these novel SARS-CoV-2 variations threatens to the substantial success made so far in restricting the spread of this viral disease, despite the extraordinary speed with which vaccines against COVID-19 have been developed and vigorous worldwide mass immunization efforts. Through mechanisms involving the dysregulated ACE 2 receptor and TMPRSS2, the SARS-CoV-2 virus has the potential to induce significant systemic disease in the GI tract, liver, biliary tract, and pancreas. Due to the observation of new and daily mutations of this dangerous virus, the definitive treatment of this disease is becoming more and more difficult and facing major challenges that it requires many clinical trials and researches.