yb-1蛋白在老年痴呆症Сhimeric模型中的作用

Institute of information technology Pub Date : 1900-01-01 DOI:10.47501/978-5-6044060-1-4.10

N. V. Bobkova, R. Poltavtseva, Daria Zhdanova, V. Kovalev, A. Chaplygina

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引用次数: 0

摘要

本文主要研究人间充质间质细胞与转基因XFAD小鼠海马原代培养的分子细胞相互作用，以及多功能YB-1蛋白对阿尔茨海默病模型动物成体神经发生龛记忆和状态的影响。结果表明，综合使用细胞疗法与YB-1联合激活阿尔茨海默病患者的代偿机制是有用的。

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THE EFFECT OF YB-1 PROTEIN IN СHIMERIC MODEL OF ALZHEIMER’S DISEASE

The paper focuses on the molecular cell interaction of human mesenchymal stromal cells with the hippocampal primary culture of transgenic XFAD mice and the effect of multifunctional YB-1 protein on the memory and state of adult neurogenesis niches in animals with a chi-meric model of Alzheimer's disease. The results suggest the usefulness of a comprehensive use of cell therapy in combination with YB-1 to activate compensatory mechanisms in patients with Alzheimer's disease.

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Institute of information technology

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