博卡拉三级保健中心缺铁性贫血儿童患病率、危险因素和血液学参数的研究

A. Paudel, K. Malla, S. Shrestha, S. Paudel, D. Paudel, R. Bastola, Yagyaraj Sigdel, R. Gurung
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引用次数: 1

摘要

缺铁性贫血(IDA)是世界上最常见的贫血。它对婴儿和儿童的身体发育、认知、行为和免疫状况产生不利影响。在尼泊尔,分析其在儿科人群中的患病率、危险因素和诊断的研究数量有限。限制止痛药的摄入,增加富含铁的食物的摄入和驱虫是疾病管理的重要决定因素。方法:于2014年12月至2016年12月在马尼帕尔教学医院儿科进行以医院为基础的前瞻性比较研究,纳入所有6个月~ 5岁贫血患儿。统计资料、临床特征和有关危险因素的信息与详细的体格检查一起被记录下来。铁谱检查证实了IDA的诊断。数据采用SPSS 21进行分析。结果:168例贫血患儿中有110例(65.45%)诊断为IDA。饮食因素、异食癖和镇痛/解热药物的摄入是主要的危险因素。IDA患者血清铁、铁蛋白、转铁蛋白饱和度低,总铁结合力高。结论:缺铁性贫血是一种常见、可预防、易治疗的疾病,但若不及时治疗,可能造成严重后果。在生命的前6个月不遵守纯母乳喂养,在第一年引入牛奶/水牛奶,异食癖和大量使用镇痛药/退烧药是主要的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study of Prevalence, Risk Factors and Hematological Parameters in Children Suffering from Iron Deficiency Anemia in a Tertiary Care Centre in Pokhara
Introduction: Iron deficiency anemia (IDA) is the most common anemia worldwide. It adversely affects the physical growth, cognition, behavior and the immune status of infants and children. There are limited number of studies in Nepal analyzing its prevalence, risk factors and diagnosis in pediatric population. Restriction of analgesics intake, increased intake of iron rich food and deworming are important determinants in the disease management. Methods: Hospital based prospective comparative study was conducted in the Department of Pediatrics in Manipal Teaching Hospital from December 2014 to December 2016 enrolling all children aged 6 months to 5 years with anemia. Demographic profile, clinical features and information regarding risk factors were noted along with detailed physical examination. Iron profile was done to confirm diagnosis of IDA. Data was analyzed using SPSS 21. Results: Out of 168 anemic children, 110 (65.45%) children were diagnosed as IDA. Dietary factors, pica and intake of analgesics/antipyretics were major risk factors. Serum iron, serum ferritin, transferrin saturation were low whereas total iron binding capacity was high in IDA. Conclusion: Iron deficiency anemia is a common, preventable and easily treatable disease which has potentially serious consequences if not treated. Non compliance to exclusive breastfeeding in the first 6 months of life, introduction of cow’s/buffalo’s milk in the first year, pica and rampant use of analgesics/antipyretics are major risk factors.  
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