镰状细胞性贫血儿童股骨头缺血性坏死的核心减压治疗

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摘要

镰状细胞性贫血(SCA)是一种遗传性血红蛋白疾病,导致红细胞镰状坏死,导致慢性溶血性贫血、血管闭塞和进行性器官损伤。无血管坏死(AVN)是镰状细胞性贫血的常见并发症。关于儿童SCA股骨颈核心减压的研究很少。许多研究是针对成年患者进行的。我们对因镰状细胞性贫血而患有AVN的儿童进行了股骨颈核心减压(CD)。在2008年至2018年期间,29例患者进行了39例髋关节手术。患者年龄在4 - 14岁之间。AVN根据Ficat放射学分类进行分类。第1、2A和2B阶段进行了操作。如果另一个髋关节是1期或2期,则进行第3期和第4期手术。我们发现手术患者与未手术患者相比有显著改善。患者在随访中以疼痛、步态、活动和放射学分级的形式进行评估。核心减压是通过不穿过头部生长板的经皮空心钻孔完成的。优良率为87%,良良率为9%,差良率为4%。我们建议在镰状细胞性贫血儿童的所有级别AVN中进行核心减压。结论镰状细胞性贫血患儿核心减压术是一种新的手术治疗方法。这是一种简单的外科手术,大多数儿科骨科医生都能做到。我们发现股骨头减压术是预防和改善儿童镰状细胞性贫血股骨头AVN临床和影像学分期的有效方法。我们发现,与成人相比,儿童核减压的效果要好得多。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Core Decompression For Treatment of Avascular Necrosis of Femoral Head In Children With Sickle Cell Anemia
Sickle cell anemia (SCA) is a hereditary hemoglobin disorder that results in sickling of the red cell, leading to chronic hemolytic anemia, vascular occlusion and progressive organ damage. Avascular necrosis (AVN) is a known and common complication in sickle cell anemia. There are very little studies addressing core decompression of femoral neck in children with SCA. Many studies are done for adult patients. We did core decompression (CD) of femoral neck in children with AVN due to sickle cell anemia .39 hips in 29 patients are done between 2008 to 2018. The patients age ranges between 4 to 14 years of age. AVN is classified according to Ficat radiological classifications. Stage 1, 2A, and 2B are operated. Stage 3 and 4 hips were operated if the other hip is stage 1 or 2. We found a significant improvement of the operated patients compared to non-operated patients. Patients were assessed in follow-up in form of pain, gait, activity and radiological grading. Core decompression is done using a percutaneous cannulated drilling that do not cross the growth plate of the head. Excellent results were found in 87%, good results in 9% and poor results in 4%. We recommend doing core decompression in all grades of AVN in sickle cell anemia children. Conclusion Core decompression in children with sickle cell anemia is a new surgical intervention. It is a simple surgical procedure that can be done by most of pediatric orthopedic surgeons. We found that core decompression is an effective method to stop and improve clinical and radiological stages of AVN of femoral head in children sickle cell anemia. We found out that core decompression in children has far much better outcome compared to adult’s core decompression.
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