局部局限性前列腺癌的自然病史综述。

The Prostate. Supplement Pub Date : 1992-01-01 DOI:10.1002/pros.2990210512

W R Fair

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引用次数: 8

摘要

前列腺癌的发病率在50岁以上的男性中急剧上升。前列腺癌的死亡率也在上升，但与发病率的上升速度不同。在美国，男性一生中患前列腺癌的风险约为1 / 11，但死于该疾病的风险约为1 / 22-33。肿瘤DNA倍体是前列腺癌生长速度的预测特征之一。二倍体肿瘤患者的预后优于非整倍体肿瘤患者，无论分期或分级如何。定义为A1期疾病(少于5%的标本癌变)的患者进展(约12%)和死亡(约3%)的风险相对较低。有证据表明经尿道前列腺切除术(TURP)在62%的病例中有效。预期治疗包括跟踪患者，必要时给予激素治疗或TURP。四项随访期为4-10年的研究表明，前列腺癌的转移率在9%至37%之间，前列腺癌的死亡率在9%至16%之间。动物研究结果表明，激素治疗只有在肿瘤植入时或植入后不久才能提高生存率，尽管它可能是有效的姑息治疗。

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The natural history of locally confined prostate cancer: a review.

The incidence of prostate cancer rises steeply in men over the age of 50 years. Mortality due to prostate cancer also increases, but not at the same rate as the incidence. In the U.S.A., a man has a lifetime risk of developing prostate cancer of about 1 in 11, but his risk of dying of the disease is about 1 in 22‐ 33.

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The Prostate. Supplement

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