基于小数据集的深度学习乳房x线照片分类

A. P. Adedigba, Steve A. Adeshinat, A. Aibinu
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引用次数: 9

摘要

乳腺癌是诊断最多的癌症之一,也是全世界妇女死亡的主要原因,仅次于肺癌。乳房x线摄影筛查是最成功的筛查技术,能够在乳房检查发现肿块生长之前检测到90%的乳腺癌。然而,乳房x光片是一种低强度图像,乳房的异质性可以使健康的乳房组织表现为癌变,这在乳腺致密的女性(40-44岁)中最常见。因此,乳房x光检查早期发现乳腺癌的敏感性估计为85-90%。这一结果可以通过深度CNN得到改善,但是,要达到良好的泛化,必须使用大容量的数据集进行训练,而乳腺摄影数据集的体积较小。在本文中,我们提出了一种用少量数据集训练深度CNN的方法,以达到高的训练效果和良好的泛化。本文提出了一种增加数据集大小和方差的增强技术,并使用增强数据集训练了五个最先进的模型。DensNet的训练和验证准确率最高(分别为99.01%和99.99%)。同时,一个参数更少的深度CNN模型SqueezeNet也显示出了很好的结果,这意味着该模型很快就可以部署到微控制器和fpga中用于临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deep Learning-based Mammogram Classification using Small Dataset
Breast Cancer is one of the most diagnosed cancer and the leading cause of death among women worldwide, second only to lung cancer. Mammographic screening has been the most successful screening technology capable of detecting up to 90% of all breast cancer even before a lump growth can be felt using breast exam. However, mammogram is a low intensity image and the heterogeneous nature of breast can make healthy breast tissue appears as cancerous, this is most common among women with dense breast (aged 40-44). Thus, the sensitivity for early detection of breast cancer from mammogram has been estimated to 85-90%. This result can be improved by Deep CNN, however, to achieve good generalization, it must be train with high voluminous dataset whereas, mammographic dataset exists in smaller volume. In this paper, we present a method of training deep CNN with few datasets to achieve high training result and good generalization. An augmentation technique that increase both size and variance of the dataset is presented herewith, the augmented dataset was used to train five state of the art models. Highest training and validation accuracy (99.01% and 99.99% respectively) were achieved with DensNet. Meanwhile, SqueezeNet, a deep CNN model with fewer parameter also shows promising result, which means soon this model can be deployed into microcontroller and FPGAs for clinical applications.
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