【我们在肾实质肿瘤转移的手术经验:平均随访时间结果】。

A Cozzoli, E Frego, G Cancarini, A Giongo, S Cosciani Cunico
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引用次数: 0

摘要

作者报告其手术治疗肾细胞癌转移的经验。从1983年1月至1989年12月,28例患者(男19例,女9例,中位年龄58岁(42-79岁))接受了同期或随后的转移性肿瘤切除术。10例患者的转移是同步发生的,而18例患者的转移是在肾切除术后28个月的游离期后出现的。恢复期一直正常,所有患者均得到控制,每半年进行一次血、尿常规检查、胸片、腹部CAT及骨扫描。10例同步转移患者中5例死亡,3例进展中,2例在平均随访36个月后发生NED。在接受异时转移手术的18例患者中,2例死亡,4例进展,12例NED(平均随访36个月)。总之,虽然同步转移的存在即使在手术切除后也是一个不利的预后因素(10例患者中有8例在转移切除术后不久死亡或进展),但异时转移手术后的结果令人鼓舞,但这种治疗的真正效果仍有待证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Our experience in surgery of metastases of parenchymal renal neoplasms: mean follow-up time results].

The Authors report their experience about surgical treatment of metastases from renal cell carcinoma. From January 1983 to December 1989, twenty eight patients, 19 males and 9 females, with a median age of 58 years (range 42-79), have been submitted to contemporary or subsequent metastasectomy. Metastases were synchronous in 10 cases, while they appeared after a free disease mean-time of 28 months after nephrectomy in 18 patients. Recovery period has always been normal and all the patients were controlled, every six months, with routine blood and urine examinations, Chest X-ray, abdominal CAT and bone scan. Among the 10 patients with synchronous metastases 5 died, 3 are in progression and 2 are NED after a mean-time follow up of 36 months. Among 18 patients who underwent surgery for metachronous metastases, 2 died, 4 are in progression and 12 NED (mean follow up of 36 months). In conclusion, while the presence of synchronous metastases is an unfavourable prognostic factor even after their surgical removal (8 out of 10 patients died or are in progression shortly after metastasectomy), results after metachronous metastases surgery are encouraging, but the real efficiency of this treatment is still to be confirmed.

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