Analisis Efektivitas Lensa Intraokular Hidrofilik dan Hidrofobik terhadap Posterior Capsule Opacification Pascaoperasi Katarak

Posterior capsule opacification (PCO) is a frequent complication from cataract surgery with intraocular lens (IOL) implantation, is capable of affecting visual acuity (VA), and arises possibly months or years after operation. Furthermore, this is efficiently mitigated with material and design developments of IOL and surgical techniques. This study aimed at comparing the effectiveness of hydrophilic to hydrophobic acrylic IOL to enhance VA and mitigate PCO and Nd:YAG laser occurrence within 3 years after cataract surgery. This research employed analytic observational method and retrospective cohort design. Also, the subjects had experienced cataract surgery and the IOL implantation at “Dr.Yap” Eye Hospital Yogyakarta between June 2016 and December 2018, met the inclusion and exclusion criteria, and gave consent. The effectivity parameters included VA, the PCO incidence, and Neodymium: Yttrium-Aluminum-Garnet (Nd: YAG) laser, analyzed using the Chi-Square test and t-test (normal distribution) and Mann-Whitney test (non-normal distribution). The result indicated hydrophobic and hydrophilic IOL possessed VA elevation of 0.68±0.44 and 0.56±0.35 respectively, with no significant difference between both groups (p=0.111). Also, the PCO occurrence in hydrophobic IOL 12 (19.7%) was significantly lower compared to hydrophilic IOL at 32 (52.5%) (p=0.022), while Nd:YAG laser in hydrophobic IOL was 3 (4.18%) lesser than the hydrophilic IOL, 15 (24.59%) (p=0.040). However, although both IOLs were effective in enhancing VA, hydrophobic IOL was better in mitigating PCO and Nd:YAG laser occurrences compared to hydrophilic IOL.