Optical Coherence Tomography (OCT) Measurements and Disability in Multiple Sclerosis (MS): Protocol of Systematic Review

Background: It is commonly used to assess the severity and functional impairments associated with multiple sclerosis (MS) using the disability scales such as the expanded disability status scale (EDSS). A number of studies have demonstrated a correlation between optical coherence tomography (OCT) measurements, which demonstrate optical neurodegeneration, and disability, though some studies failed to detect a significant correlation. Objectives: The purpose of this study is to investigate the relationship between optical coherence tomography (OCT) measurements and disability in people with multiple sclerosis (pwMS)