{"title":"耐头孢他啶铜绿假单胞菌的内酰胺酶鉴定。","authors":"Y Michel-Briand, T Nicolas, C Godard, P Plesiat","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>4.2% Pseudomonas aeruginosa strains isolated in our hospital were resistant to ceftazidime. The 174K strain was also resistant to azthreonam but susceptible to imipenem and was studied as representative of these strains. It produced a single beta-lactamase (pI 8.6) which had all the characteristics of the chromosomal beta-lactamase Id and was the only beta-lactamase present. This enzyme hydrolyses slowly ceftazidime and imipenem. It could be a factor of imipenem resistance if the antibiotic influx into the bacteria was decreased or if the beta-lactamase Id was synthesized at a high level.</p>","PeriodicalId":77264,"journal":{"name":"Microbiologica","volume":"15 1","pages":"65-9"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"beta-Lactamase Id of ceftazidime-resistant Pseudomonas aeruginosa strains.\",\"authors\":\"Y Michel-Briand, T Nicolas, C Godard, P Plesiat\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>4.2% Pseudomonas aeruginosa strains isolated in our hospital were resistant to ceftazidime. The 174K strain was also resistant to azthreonam but susceptible to imipenem and was studied as representative of these strains. It produced a single beta-lactamase (pI 8.6) which had all the characteristics of the chromosomal beta-lactamase Id and was the only beta-lactamase present. This enzyme hydrolyses slowly ceftazidime and imipenem. It could be a factor of imipenem resistance if the antibiotic influx into the bacteria was decreased or if the beta-lactamase Id was synthesized at a high level.</p>\",\"PeriodicalId\":77264,\"journal\":{\"name\":\"Microbiologica\",\"volume\":\"15 1\",\"pages\":\"65-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbiologica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbiologica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
beta-Lactamase Id of ceftazidime-resistant Pseudomonas aeruginosa strains.
4.2% Pseudomonas aeruginosa strains isolated in our hospital were resistant to ceftazidime. The 174K strain was also resistant to azthreonam but susceptible to imipenem and was studied as representative of these strains. It produced a single beta-lactamase (pI 8.6) which had all the characteristics of the chromosomal beta-lactamase Id and was the only beta-lactamase present. This enzyme hydrolyses slowly ceftazidime and imipenem. It could be a factor of imipenem resistance if the antibiotic influx into the bacteria was decreased or if the beta-lactamase Id was synthesized at a high level.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
