用熔融沉积模型制造组织工程支架的可行性

The Seventh Australian and New Zealand Intelligent Information Systems Conference, 2001 Pub Date : 1900-01-01 DOI:10.1109/ANZIIS.2001.974118

M. H. Too, K. Leong, C. Chua, C. Cheah, S. L. Ho

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引用次数: 8

摘要

研究了利用熔融沉积建模(FDM)工艺制造用于组织工程(TE)目的的三维(3-D)非随机多孔支架的可行性。对FDM制件的结构特征，即三维孔隙连通性、孔隙率、孔径和力学性能进行评价，以确定其作为TE支架的适用性。本文介绍了FDM工艺参数对这些结构特性的影响。从研究中发现，FDM工艺能够很好地控制和再现所需的零件几何形状、孔隙度和微观结构。FDM工艺参数对零件微观结构的影响很大，为用户提供了改变制造零件结构特征的灵活性和便利性，以满足TE支架的特定结构和功能要求。

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Feasibility of tissue engineering scaffold fabrication using fused deposition modelling

The feasibility of fabricating three-dimensional (3-D) non-random porous scaffolds for Tissue Engineering (TE) purposes using the Fused Deposition Modelling (FDM) process is investigated. The structural characteristics of FDM fabricated parts, namely, 3-D pore inter-connectivity, porosity, pore size and mechanical properties were evaluated, to determine their suitability for use as TE scaffolds. The influence of FDM process parameters on these structural characteristics is presented in this paper. From the investigations, the FDM process is found to be highly capable of providing good control and reproducibility of the desired part geometry, degree of porosity and microstructure. The high influence exerted by the FDM process parameters on the part microstructure, offers the user flexibility and ease of varying the structural characteristics of built parts to meet specific structural and functional requirements of TE scaffolds.

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来源期刊

The Seventh Australian and New Zealand Intelligent Information Systems Conference, 2001

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