比索甲状腺疾病发病率及外科治疗的回顾性研究

D. Bawa, Saleem Khan, Y. Khalifa, Shashi Sharma, Amal A Alghamdi, H. Albishi, Nasser Al Tufail
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摘要

背景:尽管超过15年的全国运动增加膳食碘补充,但比沙甲状腺肿的患病率很高。原因是多方面的。它与非肿瘤性和肿瘤性疾病有关。外科治疗已经发展了很多年。目的:描述比沙地区甲状腺肿的病理类型及其治疗方法,并讨论当前的手术注意事项。方法:回顾性分析339例经FNAC和/或组织病理学检查诊断的甲状腺肿患者,并进行手术或非手术治疗。结果:339例患者中,女性280例(82.6%),男性59例(17.4%)。年龄范围7 ~ 94岁,平均39.18±13.87岁。多结节性甲状腺肿大138例(40.7%),胶质性甲状腺肿大82例(24.2%),弥漫性甲状腺肿大8例(2.4%),单发甲状腺结节40例(11%),甲状腺结节10例(2.9%),甲状腺囊肿14例(4.1%),桥本甲状腺炎20例(5.9%),de Quervain甲状腺炎2例(0.6%)。良性甲状腺肿瘤包括25例(7.4%)滤泡性腺瘤和11例(3.2%)甲状腺细胞性腺瘤。甲状腺恶性疾病包括甲状腺乳头状癌18例(5.3%)、甲状腺乳头状/滤泡混合型癌7例(2.1%)、甲状腺滤泡/乳头状混合型癌1例(0.3%)、甲状腺滤泡型癌3例(0.9%)。甲状腺全切除术128例(37.1%),甲状腺切除术70例(20.6%),甲状腺次全切除术10例(2.9%),甲状腺近全切除术5例(1.5%)。125例(36.9%)患者未行手术。总并发症发生率为14.5%。结论:尽管多年的膳食碘补充运动,甲状腺疾病仍然普遍存在。甲状腺全切除术后的并发症发生率很高,指南也在不断变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retrospective Study on the Incidence of Thyroid Disorders in Bisha and Evolving Surgical Management Considerations
Background: There is a high prevalence of goiter in Bisha despite more than 15 years of the national campaign for increased dietary iodine supplementation. The cause is multifactorial. It is associated with non-neoplastic and neoplastic conditions. Surgical management has evolved over many years. Purpose: To describe the pathological types of goiter in Bisha along with their management and to discuss current surgical considerations. Methodology: A retrospective review of 339 patients with goiter diagnosed by FNAC and or histopathological examination and managed surgically or non-surgically. Results: There were 339 patients, of which 280 (82.6%) were females and 59 (17.4%) males. Age range was seven to 94 years with a mean of 39.18 ± 13.87 years. There were 138 (40.7%) multinodular goiters, 82 (24.2%) colloid goiters, 8 diffuse goiters (2.4%), 40 (11%) solitary thyroid nodules, 10 thyroid nodules (2.9%), 14 thyroid cysts (4.1%), 20 Hashimoto’s thyroiditis (5.9%) and two de Quervain’s thyroiditis (0.6%). Benign thyroid neoplasms comprised of 25 (7.4%) follicular adenomas and 11 (3.2%) Hürthle cell adenomas. Malignant thyroid disorders consisted of 18 (5.3%) papillary thyroid cancers, 7 (2.1%) mixed papillary/ follicular thyroid cancers, one (0.3%) mixed follicular/ papillary thyroid cancer, and three (0.9%) follicular thyroid cancers respectively. There were 128 (37.1%) total thyroidectomies, 70 (20.6%) hemithyroidectomies, 10 (2.9%) subtotal thyroidectomies and, 5 (1.5%) near-total thyroidectomies. There were 125 (36.9%) patients who had no surgery. The overall complication rate was 14.5%. Conclusion: Thyroid disorders are still prevalent despite years of dietary iodine supplementation campaigns. The rate of complications following total thyroidectomy is significant and guidelines are changing.
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