儿童急性中耳炎的治疗(全身性抗生素和局部减充血剂与单用全身性抗生素)

Edrees M. Hussain, M. Yaseen
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引用次数: 0

摘要

背景:减充血剂广泛应用于急性中耳炎的全身或局部鼻用治疗,但其有效性仍存在争议。本研究的目的是评估局部减充血剂治疗急性中耳炎的有效性及其在急性中耳炎发作后中耳积液解决中的作用。对象和方法:本研究涉及2015-2017年期间在埃尔比勒Rizgary教学医院进行的100名需要抗生素治疗的急性中耳炎儿童,年龄从4-12岁不等,男女均有。患者随后分为两组进行治疗。A组患者口服复方阿莫昔拉夫、口服扑热息痛、外用木美唑啉滴鼻治疗。B组给予相同抗生素治疗,但不局部滴鼻木甲咪唑啉。对这些儿童进行了为期3个月的5次随访;在第一次和第二次随访中,对儿童进行临床检查,以了解急性感染的体征和症状是否有所改善。在最后三次就诊中,通过耳镜检查和鼓室测量检查对患儿中耳积液进行了随访。对患儿第一次和第五次就诊进行纯音听力学(PTA)测试,了解患儿两次就诊间听力增加情况及A组与b组的差异。结果:患儿平均年龄+ SD为7.26 + 2.4岁,年龄范围4 ~ 12岁。中位数为7年。58%的患者是男孩,42%的患者是女孩。在第一次访问中,我们发现A组的效果更好,疼痛缓解接近显著(p=0.067)。在随后的随访中,我们发现两组患者的症状都得到了很好的缓解,而a组的效果没有明显改善。结论:使用局部减充血剂治疗AOM没有明显的益处。杜霍克医学杂志2018;12 (1): 96-105
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TREATMENT OF ACUTE OTITIS MEDIA IN CHILDREN (SYSTEMIC ANTIBIOTIC AND TOPICAL NASAL DECONGESTANT VERSUS SYSTEMIC ANTIBIOTIC ALONE)
Background: decongestants whether systemic or topical nasal are widely used in the treatment of acute otitis media but there is still controversy about their effectiveness. The aim of this study is to evaluate the effectiveness of topical nasal decongestants in the treatment of acute otitis media and their role in the resolution of middle ear effusion after acute otitis media attack. Subject and Methods: The current study involved 100 children ranging from 4-12 years of both sexes with acute otitis media that need antibiotics in treatment and the study done in Rizgary teaching hospital in Erbil during the period of 2015-2017. Patients subsequently divided into two groups for treatment. Group A treated with oral co-amoxiclav, oral paracetamol, and topical nasal xylometazoline drop. Group B treated with the same antibiotic but without topical nasal xylometazoline drop. The children are followed up three months by 5 visits; in the first and second follow up visits the children are examined clinically for the improvement in the signs and symptoms of acute infection. In the last three visits the children are followed up for the resolution of middle ear effusion by otoscopic examination and tympanometry test. Pure Tone Audiometry (PTA) test done for children in the first and fifth visits, to know the hearing gain between the two visits and the difference between group A and group B. Results: The mean age + SD of the children were 7.26 + 2.4 years, ranging from 4 to 12 years. The median was 7 years. 58% of the patients were boys and 42% were girls. In the first visit, we found better results in group A that was near significant for pain relief (p=0.067). During subsequent visits we found good resolution in both groups with non significant better results in group A. Conclusions: there is no significant benefit from the use of topical nasal decongestant in the treatment of AOM. Duhok Med J 2018; 12 (1): 96-105
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