地塞米松治疗慢性硬膜下血肿的疗效观察

Y. Navruz, Erek Öztürk, A. Iplikcioglu
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引用次数: 1

摘要

目的:在本研究中,我们旨在分析慢性硬膜下血肿患者的硬膜下积液特性和术后随访,根据是否使用地塞米松治疗随机分为两组。材料与方法:本研究纳入42例慢性硬膜下血肿患者。根据地塞米松治疗情况将患者分为两组。21例患者采用地塞米松治疗。所有患者均行钻孔开颅术,并建立封闭系统引流。分析术前和术后引流硬膜下液的量和性质(血红蛋白、总蛋白和白蛋白水平)。颅脑电脑断层扫描进行随访,并控制硬膜下空间积液的存在。结果:与术前实验室结果相比,两组均有统计学意义的降低。然而,与非地塞米松组相比,地塞米松组的下降更为显著。随访的计算机断层扫描结果显示,地塞米松组出现罕见的新硬膜下积液。结论:我们的研究结果表明,慢性硬膜下血肿患者手术加地塞米松治疗比不加地塞米松治疗有更好的临床效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effects of Dexamethasone Used in the Treatment of Chronic Subdural Hematoma
Aim: In this study, we aimed to analyze the properties of drained subdural fluid and post-operative follow-up of patients with chronic subdural hematoma subdivided randomly into two groups according to presence or absence of dexamethasone treatment. Material and Methods: 42 patients with chronic subdural hematoma were involved in this study. The patients were divided into two groups according to dexamethasone treatment. 21 of the patients were treated with dexamethasone. All patients underwent burr hole craniotomy and a closed system drainage was constructed. The amount and properties of per-operative versus post-operative drained subdural fluid (hemoglobin, total protein and albumin levels) were analyzed. Cranial computerized tomography scans were used for follow-up and presence of fluid collection in subdural space was controlled. Results: When compared to per-operative laboratory results, statistically significant decrease was observed in both groups. However, the decrease in dexamethasone group was more significant compared to none-dexamethasone group. Follow-up computerized tomography results showed rare new subdural fluid collection development in dexamethasone group. Conclusion: As a result, Our findings suggest that surgery with dexamethasone treatment in chronic subdural hematoma patients has a more favourable clinic result compared to surgery without dexamethasone treatment.
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