利用黄藤叶乙醇提取物和金缕草抗肥胖的研究

Chandana Pasupuleti, Chimata Manisha
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引用次数: 0

摘要

肥胖是一种复杂的疾病,其特征是身体脂肪过多。它会增加患其他疾病和疾病的风险,比如糖尿病、高血压和心脏病。当我们的身体质量指数达到或超过30kg/m2时,我们就认为存在肥胖。今天,更多的疾病是用传统药物治疗的——主要是草药——而不是对抗疗法药物。与草药相比,对抗性药物具有更高的副作用。本研究的目的是制备和评价用黄藤叶和黄藤叶的乙醇提取物制备的中药片剂。采用湿造粒法制备该制剂。对制备的配方进行了预压缩参数和后压缩参数的评价。计算表明,允许的预压缩和后压缩参数在一定范围内。在IEC稳定性研究前后,黄藤黄(HCA)含量测定结果分别为49.78%和49.69%(离子交换色谱法)。紫外分光光度计稳定性测定前后,康菲乐酮的含量分别为12.38%和12.26%。根据研究结果,发现该配方相当稳定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utilising the Ethanolic Extracts of Leaves Garcinia Cambogia and Commiphora Mukul Herbal Pills Prepared for Treating Anti-Obesity Effects
A complex disorder called obesity is characterised by an excessive quantity of bodily fat. It raises the risk of developing other illnesses and medical conditions like diabetes, high blood pressure, and heart conditions. When our BMI is 30kg/m2 or greater, obesity is considered to exist. Today, more ailments are treated with traditional medicines—mostly herbal in nature—than with allopathic drugs. Compared to herbal drugs, allopathic drugs have higher side effects. The purpose of the current work is to create and assess the herbal tablet prepared using an ethanolic extract of Commiphoramukul and Garcinia cambogia leaves. Wet granulation was used to manufacture the formulation. Both the pre-compression parameter and the post-compression parameter of the prepared formulation were assessed. The calculation demonstrated that the permissible pre- and post-compression parameter is within bounds. Before and after the IEC's stability investigation, the Garcinia cambogia (HCA) content assay yielded results of 49.78% and 49.69%, respectively (Ion Exchange Chromatography). The content of Commiphoramukul (guggulsterones) was 12.38% and 12.26% before and after the UV Spectrophotometer stability investigation. The formulation was found to be reasonably stable based on the findings.
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