同轴探头感应半径内组织介电贡献的建模

A. L. Gioia, M. O’halloran, E. Porter
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引用次数: 2

摘要

生物组织的介电特性是电磁医疗设备设计的基础。组织介电特性的测量通常采用开放式同轴探头技术。虽然对同质生物组织进行电介质表征的过程很简单;异质组织的严格介电特性需要进行测量后的组织学分析,以准确地将测量的介电特性与组织含量联系起来。在这种程度上,至关重要的是量化探针的传感体积,包括传感半径和传感深度,并研究不同组织类型如何根据它们在传感体积内的分布对获得的介电信号做出贡献。由于一些研究模拟了呈现纵向非均匀的组织样品的介电贡献,在这项工作中,首次模拟了径向非均匀样品中组织的介电贡献。发现单个组织对获得的介电数据的贡献与每个组织在径向非均匀样品中占据的体积之间存在非线性关系。这项工作能够基于对组成组织的了解,预测具有径向非均质样品的介电常数,并为非均质样品的准确介电特性提供基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modelling of Tissue Dielectric Contribution Within the Sensing Radius of a Coaxial Probe
The dielectric properties of biological tissues are fundamental for the design of electromagnetic medical devices. Tissue dielectric properties are generally measured using the open-ended coaxial probe technique. While the procedure to dielectrically characterise homogeneous biological tissues is straightforward; rigorous dielectric characterisation of heterogeneous tissues requires conducting a post-measurement histological analysis to accurately associate the measured dielectric properties to the tissue content. To this extent, it is crucial to quantify the sensing volume of the probe, consisting of the sensing radius and sensing depth, and examine how different tissue types contribute to the acquired dielectric signal depending on their distribution within the sensing volume. Since a few studies have modelled the dielectric contribution of tissue samples presenting longitudinal heterogeneities, in this work, the dielectric contribution of tissues within radially heterogeneous samples is modelled for the first time. A nonlinear relationship is found between the contribution of individual tissues to the acquired dielectric data and the volume that each tissue occupies within the radially heterogeneous sample. This work enables prediction of the permittivity of a sample with radial heterogeneities, based on knowledge of the constituent tissues, and provides the basis for accurate dielectric characterisation of heterogeneous samples.
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