利用电阻抗谱(EIS)系统对细胞异常进行建模和表征,用于预测乳腺癌的初步分析

N. Amin, S. Rayhan, Asif Ahmed Anik, Rayeesa Jameel
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引用次数: 7

摘要

在孟加拉国,乳腺癌占妇女死亡人数的69%。由于人们不了解、对医疗缺乏信心、筛查不当、虐待以及缺乏前往机构治疗和管理的动力,这一数字日益增加。大众可获得的最常见的乳腺癌检测机制是乳房x光检查,然而,与之相关的一些风险,如直接暴露于辐射中。乳房x光检查也相当昂贵,该国的广大人口无法轻易获得。电生物阻抗(EBI)分析可用于乳腺癌的检测和筛查。当在不同的频率点进行EBI测量时,它被称为电阻抗谱(EIS),它可以作为一种当地可用且廉价的乳腺癌检测筛查工具。本文使用一个已建立的生物组织模型来研究EIS装置的有效性,该装置可以用当地可用的简单电子元件构建。测量了正常组织和癌组织模型的阻抗和相位角,并与已知的参考值进行了比较。结果表明,EIS装置工作令人满意,并进行了微调,将以可承受的成本提供必要的医疗设施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modelling and characterization of cell abnormality using electrical impedance spectroscopy (EIS) system for the preliminary analysis to predict breast cancer
In Bangladesh, breast cancer accounts for 69% death of women. This number increases day by day due to unawareness of the people, lack of confidence about medical treatment, improper screening, maltreatment and lack of motivation to go for institutional treatment and management. The most common form of detection mechanism for breast cancer available to the mass people is mammography, however, several risks, such as direct exposure of radiation are associated with it. Mammography tests are also quite expensive which cannot be readily availed by the mass population of the country. Electrical Bio-impedance (EBI) analysis can be used in breast cancer detection and screening. When EBI measurements are taken at various frequency points it is called Electrical Impedance Spectroscopy (EIS) which can be used as a locally available and cheap screening tool for breast cancer detection. This paper uses an established model of a biological tissue to study the effectiveness of an EIS device that can be constructed with simple electrical components available locally. The impedance and phase angles of both models of normal tissue and cancerous tissue were measured and compared with a known reference. Results showed that the EIS device works satisfactorily and with fine-tuning, will provide the necessary medical facility at an affordable cost.
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