果蝇雄性生殖细胞过渡带组装及其对轴突形成的贡献

The Journal of Cell Biology Pub Date : 2016-09-26 DOI:10.1083/jcb.201603086

Jennifer Vieillard, M. Paschaki, Jean-Luc Duteyrat, Céline Augière, Elisabeth Cortier, Jean-André Lapart, Joëlle Thomas, B. Durand

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引用次数: 51

摘要

纤毛过渡带(Ciliary transition zone, TZ)的组成复杂且不完全清楚。Vieillard等人的研究表明，果蝇Cby和Dila合作组装TZ和膜帽，并通过驱动蛋白-13进行微管重塑，这是雄性生殖细胞轴突形成所必需的。

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Transition zone assembly and its contribution to axoneme formation in Drosophila male germ cells

Ciliary transition zone (TZ) assembly is complex and incompletely understood. Vieillard et al. show that Drosophila Cby and Dila cooperate to assemble the TZ and membrane cap, which, together with microtubule remodeling by kinesin-13, is required for axoneme formation in male germ cells.

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The Journal of Cell Biology

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