烟草消费习惯在癌前病变中的作用:一项横断面研究

N. Shah, Y. Shah, Drupad Supeda, Pawan Tadwala, M. Thaker, J. Chhaya, N. Pandit
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引用次数: 0

摘要

口腔癌在印度和世界范围内都很常见,并且呈上升趋势。吸烟和无烟烟草在世界范围内都在增加。常见的口腔癌前病变有口腔白斑、红斑、口腔癌和口腔黏膜下纤维化(OSMF)。筛查是发现此类病变的最佳工具。目前的研究是为了了解烟草消费的流行程度,并检查烟草消费者的口腔,以发现工作人员的癌前病变。方法:采用横断面研究方法,对三级医院工作人员进行调查。该研究从2017年5月到2017年10月进行了6个月。该研究获得了机构伦理委员会的伦理许可。选取医院3级和4级工作人员作为研究参与者,涉及两性并提供书面知情同意。采用随机抽样方法,从提供的抽样框架中抽取120名工作人员参加研究。既往有任何全身性疾病、免疫缺陷或免疫抑制患者住院史的研究参与者,以及已被诊断为身体任何部位有恶性癌症病变的参与者被排除在外。结果:120名研究对象中,31 - 40岁年龄组占40%,男性占多数(80%),信仰印度教(90.83%)。任何形式的烟草消费流行率为85%;其中使用无烟烟草的占43.33%,同时吸烟的占10.83%,两者兼有的占30.83%。口腔黏膜下纤维化(OSMF)是本研究中最常见的癌前病变(70.58%),其次是白斑(16.67%)。结论:目前的研究显示出较高的患病率。迫切需要在各个层面制定戒毒计划。那些有癌前病变的人也需要警告和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Tobacco Consumption Habits in the Causation of Precancerous Lesions: A Cross Sectional Study
Oral carcinoma is quite common and increasing trend in India and worldwide. Smoking and smokeless tobacco both are increasing worldwide. The common oral precancerous lesions are oral leukoplakia, erythroplakia, nicotina palati and oral sub mucous fibrosis (OSMF). Screening is best tool to find out such lesions. The current study is conducted to know the prevalence of tobacco consumption and also to examine oral cavity of tobacco consumer to detect precancerous lesions among the staff. Method: The present study was cross sectional study carried out tertiary care hospital staff. The study was conducted over a period of 6 month from May 2017 to October 2017. Ethical clearance for study was obtained from Institutional Ethical Committee. The staff members of class 3 and class 4 of hospital were taken as a study participants involving both of sex and who provided written informed consent. Sample of 120 staff members were enrolled for the study from provided sampling frame with the use of random sampling method. Study participants with previous history of hospital admission for any systemic illness, immunodeficiency or immunosuppressive patients, and participants who already diagnosed to have malignant cancer lesions in any part of body were excluded. Result: Of 120 study participants, 40% were belongs to 31 – 40 years of age group and majority were male (80%) and belonged to Hindu (90.83%) religion. The prevalence of tobacco consumption in any of form is 85%; of them 43.33% used smokeless tobacco and 10.83% used to with smoking and 30.83% had both forms of tobacco. Oral Sub Mucosal Fibrosis (OSMF) was the most common (70.58%) precancerous lesion found in the present study, followed by leukoplakia (16.67%). Conclusion: Current study revealed the high prevalence. There is urgent need to plan de-addiction at various level. Also those having the precancerous lesion need to warn and treat accordingly.
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