用于DNA重复序列检测的内存专用点图分析

P. Pop
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引用次数: 1

摘要

DNA重复序列被认为在基因组进化和严重疾病的表现中起着重要作用。许多寻找重复序列的方法使用距离、相似性和一致性序列来生成候选序列。本文介绍了使用专用的数字表示和映射算法(使用DNA距离和共识类型)以及结合图像处理技术的内存点图分析获得的结果,以视觉隔离不同长度的DNA重复序列的位置。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In-memory dedicated dot-plot analysis for DNA repeats detection
DNA repeats are believed to play significant roles in genome evolution and manifestation of severe diseases. Many of the methods for finding repeated sequences use distances, similarities and consensus sequences to generate candidate sequences. This paper presents results obtained using a dedicated numerical representation with a mapping algorithm (using DNA distances and consensus types) and an in-memory dot-plot analysis combined with image processing techniques, to visual isolate the positions of DNA repeats with different lengths.
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