具有选择性渗透的间隙结通道的分子通信模型

Yiqun Yang, C. Yeo
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引用次数: 0

摘要

随着生物和纳米领域的快速发展,新的通信方法为各种研究问题提供了新的解决方案。由于纳米机器结构简单,尺寸有限,纳米网络与传统网络有着明显的区别。因此,探索性的分析和理论是值得期待的。分子通信涉及纳米尺度的生物成分,为医学、环境和农业研究提供了一种更兼容的方法。钙离子(Ca2+)是体内细胞中最重要的通用第二信使之一,积极参与细胞活动的调节。在本文中,我们建立了通过缝隙连接通道的分子通信系统的模型。我们给出了具有不同渗透率的图案细胞的模拟结果。我们分析了肌醇(1,4,5)-三磷酸(IP3)扩散诱导的细胞间钙波的传播特性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Molecular communication model through gap junction channel with selective permeabilities
With rapid development in biological and nano areas, new communication methods promise novel solutions for various research issues. Due to the simple structure and the limited size of nanomachines, nanonetworks have conspicuous differences from traditional networks. Hence exploratory analysis and theory are expected. Molecular communication, which involves biological components in nanoscale, provides a more compatible approach to medical, environmental and agricultural research. Calcium ion (Ca2+), which is one of the most important universal second messengers in vivo cells, participates actively in the regulation of cellular activities. In this paper, we model the molecular communication system through gap junction channels. We present simulation results for patterned cells with different permeabilities. We analyze the propagation characteristics of intercellular calcium waves which are induced by the diffusion of inositol (l, 4, 5)-trisphosphate (IP3).
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