阻塞性睡眠呼吸暂停患者自发觉醒和呼吸觉醒后RR和QT间期的变化

M. Baumert, J. Smith, P. Catcheside, D. McEvoy, D. Abbott, E. Nalivaiko
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引用次数: 8

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见的疾病,与高血压和室性心律失常有关。本研究的目的是探讨OSA患者呼吸和自发觉醒后RR和QT间期的变化。我们对20个病人进行了夜间睡眠研究。呼吸障碍指数的平均值为49,范围为28。在第二阶段睡眠中,在30秒的时间内分析心电图。在调查的187次唤醒中(120次呼吸性对67次自发性),大量唤醒与RR间期缩短相关(64%)。18%的RR间隔时间延长,自发觉醒期间的RR间隔时间明显增加(13%对27%)。同样,觉醒后QT间期缩短(65%)。自发觉醒和呼吸觉醒之间无显著差异。综上所述,自发性和呼吸性觉醒导致心率和心室复极的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in RR and QT intervals after spontaneous and respiratory arousal in patients with obstructive sleep apnea
Obstructive sleep apnea (OSA) is a common disorder that has been associated with hypertension and ventricular arrhythmias. The aim of this study was to investigate changes in RR and QT intervals after respiratory and spontaneous arousals in patients with OSA. We conducted overnight sleep studies in 20 patients. The mean and range of respiratory disturbance index were 49 plusmn 28 and respectively. During stage 2 sleep, ECGs were analyzed over a period of 30 seconds. From the 187 arousals investigated (120 respiratory vs. 67 spontaneous) a significant number were associated with a RR interval shortening (64%). Eighteen percent of the RR intervals were prolonged, with a significantly higher number during spontaneous arousals (13% vs. 27%). Similarly, QT intervals shortened after arousal (65%). But there were no significant differences between spontaneous and respiratory arousals. In conclusion, spontaneous and respiratory arousals lead to changes in heart rate and ventricular repolarization.
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