{"title":"Vimpat治疗顽固性癫痫的疗效和耐受性","authors":"Batool F. Kirmani, D. Mungall","doi":"10.5580/2cf2","DOIUrl":null,"url":null,"abstract":"Epilepsy is a complex neurological disorder caused by abnormal, sudden, excessive electrical discharges of the neurons in the brain. There are many different seizure types and epileptic syndromes, but all involve abnormal electrical activity. It has been shown that 30% of patients with epilepsy remain medically intractable. For these patients, many of whom have failed multiple classes of antiepileptic drugs (AEDs) and/or surgical procedures, newly FDAapproved drugs are of particular interest.","PeriodicalId":232166,"journal":{"name":"The Internet Journal of Neurology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficacy and Tolerability of Vimpat in Patients with Intractable Epilepsy\",\"authors\":\"Batool F. Kirmani, D. Mungall\",\"doi\":\"10.5580/2cf2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Epilepsy is a complex neurological disorder caused by abnormal, sudden, excessive electrical discharges of the neurons in the brain. There are many different seizure types and epileptic syndromes, but all involve abnormal electrical activity. It has been shown that 30% of patients with epilepsy remain medically intractable. For these patients, many of whom have failed multiple classes of antiepileptic drugs (AEDs) and/or surgical procedures, newly FDAapproved drugs are of particular interest.\",\"PeriodicalId\":232166,\"journal\":{\"name\":\"The Internet Journal of Neurology\",\"volume\":\"16 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-01-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet Journal of Neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/2cf2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet Journal of Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/2cf2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Efficacy and Tolerability of Vimpat in Patients with Intractable Epilepsy
Epilepsy is a complex neurological disorder caused by abnormal, sudden, excessive electrical discharges of the neurons in the brain. There are many different seizure types and epileptic syndromes, but all involve abnormal electrical activity. It has been shown that 30% of patients with epilepsy remain medically intractable. For these patients, many of whom have failed multiple classes of antiepileptic drugs (AEDs) and/or surgical procedures, newly FDAapproved drugs are of particular interest.