聚乳酸封装亚甲基蓝作为光学相干层析成像造影剂

2019 IEEE Photonics Conference (IPC) Pub Date : 2019-09-01 DOI:10.1109/IPCon.2019.8908365

J. Palma, W. Kim, M. Serafino, S. Kim, J. Jo, P. Charoenphol, B. Applegate

{"title":"聚乳酸封装亚甲基蓝作为光学相干层析成像造影剂","authors":"J. Palma, W. Kim, M. Serafino, S. Kim, J. Jo, P. Charoenphol, B. Applegate","doi":"10.1109/IPCon.2019.8908365","DOIUrl":null,"url":null,"abstract":"Methylene Blue (MB), an FDA approved dye, has been widely used in clinical applications. However, issues remain for its use as contrast agent: production of 1O2, reduction into leuco-MB, and nonspecific tagging. These issues were addressed by loading MB into Poly-Lactic-co-Glycolic Acid (PLGA) particles.","PeriodicalId":314151,"journal":{"name":"2019 IEEE Photonics Conference (IPC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PLGA Encapsulated Methylene Blue as a Contrast Agent for Optical Coherence Tomography\",\"authors\":\"J. Palma, W. Kim, M. Serafino, S. Kim, J. Jo, P. Charoenphol, B. Applegate\",\"doi\":\"10.1109/IPCon.2019.8908365\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Methylene Blue (MB), an FDA approved dye, has been widely used in clinical applications. However, issues remain for its use as contrast agent: production of 1O2, reduction into leuco-MB, and nonspecific tagging. These issues were addressed by loading MB into Poly-Lactic-co-Glycolic Acid (PLGA) particles.\",\"PeriodicalId\":314151,\"journal\":{\"name\":\"2019 IEEE Photonics Conference (IPC)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2019 IEEE Photonics Conference (IPC)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IPCon.2019.8908365\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2019 IEEE Photonics Conference (IPC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IPCon.2019.8908365","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

亚甲基蓝(MB)是一种经FDA批准的染料，已广泛应用于临床。然而，它作为造影剂仍然存在一些问题:产生1O2，还原成白细胞mb，以及非特异性标记。通过将MB加载到聚乳酸-羟基乙酸(PLGA)颗粒中来解决这些问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

PLGA Encapsulated Methylene Blue as a Contrast Agent for Optical Coherence Tomography

Methylene Blue (MB), an FDA approved dye, has been widely used in clinical applications. However, issues remain for its use as contrast agent: production of 1O2, reduction into leuco-MB, and nonspecific tagging. These issues were addressed by loading MB into Poly-Lactic-co-Glycolic Acid (PLGA) particles.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

2019 IEEE Photonics Conference (IPC)

自引率

0.00%

发文量