用于测量复杂介质中超低浓度分析物的多模态纳米结构

2020 International Conference Laser Optics (ICLO) Pub Date : 2020-11-02 DOI:10.1109/ICLO48556.2020.9285418

V. A. Bragina, A. G. Burenin, N. V. Zhukov

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引用次数: 0

摘要

建立了基于多模态纳米结构的高灵敏度横向流动检测方法，用于复杂基质中葡萄球菌肠毒素B的检测。为了优化检测参数，免疫试剂的动力学表征，固定界面和纳米颗粒的选择，使用了改进的无标记光学生物传感器。开发的检测方法快速，易于使用，兼容可负担的消耗品和不同的样品体积，不需要样品预处理。

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Multi-Modal Nanostructures for Measuring Ultra-Low Concentrations of Analytes in Complex Mediums

Highly-sensitive lateral flow assay based on multi-modal nanostructures has been developed for detection of staphylococcal enterotoxin B in complex matrices. For optimization of assay parameters, kinetic characterization of immunoreagents, selection of immobilization interfaces and nanoparticles, modified label-free optical biosensors were used. The developed assay is rapid, easy-to-use, compatible with affordable consumables and different sample volumes, does not require sample pretreatment.

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2020 International Conference Laser Optics (ICLO)

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