低血糖的法医学-3

D. C. Beatty, C. G. Yap
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摘要

“环境富集”(EE)是治疗2型糖尿病相关并发症的一种已被证实的替代疗法。EE保存了大脑中的浦肯野细胞。后者是预防糖尿病相关精神障碍的一种有希望的治疗方法。感觉神经在高血糖环境中受损的风险更高,从而导致糖尿病性神经病变。患者的下肢失去知觉,因为他们感觉不到疼痛,因此很容易受伤,这是组织损伤的警告信号。这会导致灾难性的后果,因为高血糖会使伤口难以愈合。气性坏疽和组织坏死发展,导致唯一的手段是截肢和生活改变的挑战。然而,糖尿病的早期诊断对于延长糖尿病及其并发症的发病至关重要。迄今为止,已经报道了许多候选的早期生物分子,它们有望成为糖尿病的早期指标。然而,这一研究领域的进展尚未被报道。糖尿病和甲状腺疾病(包括阿狄森氏病)的整体饮食、生活方式、心理健康和临床治疗对患者的福利起着重要作用。不幸的是,许多病人英年早逝,或者一生都背负着维多利亚时代的耻辱,不得不治疗一种无法治愈的疾病。这不是2006年9月赫特福德郡保险经纪人在无知中提出的一个笑话,他把患有神经性低血糖症的糖尿病描述为一个笑话和胡说八道。这导致了严重危及生命的糖尿病和内分泌疾病并发症的法律公正受到阻碍,现在在2023年,一名年轻的法律学生不幸死亡,可能是临床未确诊的外耳炎和骨髓炎。患者需要临床医生处方胰岛素证明临床尊重和理解在英国法律自1994年以来一直被误解,可悲的后果在本调查。今天,在恢复和管理2020年COVID-19大流行的过程中,我们提出了新的福利理念。很高兴能够分享一些基于44年T1糖尿病经验的未来研究的最新工作,并受到浦肯野细胞环境福利的赞扬。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Forensic Law in Hypoglycaemia-3
“Environmental Enrichment” (EE) is a proven alternative therapy for Type 2 diabetes related complications. EE preserves the Purkinje cells in the brain. The latter is a promising therapy for prevention of diabetes related mental disorders. Sensory nerves are at higher risk of damage in the hyperglycemic milieu leading to diabetic neuropathy. Patients lose sensation in their lower extremities making them vulnerable to injury because they do not feel the pain, which is a warning sign of tissue damage. That can lead to catastrophic outcomes because with high blood glucose, wounds get difficult to heal. Gas gangrene and tissue necrosis develop, leading to the only resort being amputation and life change challenge. Early diagnosis of diabetes is nevertheless crucial in prolonging the onset of diabetes and its complication. To date many candidate early biomolecules have been reported which are promising early indicators for diabetes. However, advancement in this field of research has not been reported. Holistically diet, lifestyle, mental health and clinical treatment of Diabetes and Thyroid Disease, including Addison’s Disease, plays an important role in patient welfare. Tragically many patients die young or go through life suffering from the old Victorian Stigma of being tainted by having to treat an uncurable illness. This is not a joke as suggested in September 2006 in ignorance by a Hertfordshire Insurance Broker describing Diabetes with Neuroglycopenia as a Joke and Nonsense. This caused Obstructed Justice in Law of a critical life-threatening complication of Diabetes and Endocrinology Disease in Hypoglycaemia Unawareness and now in 2023 Otitis Externa and Osteomyelitis as disclosed in a tragic young law student death with likely clinically undiagnosed Otitis Externa and Osteomyelitis. A patient requiring clinician prescribed Insulin justifies clinical respect and understanding in English Law which has been misunderstood since 1994 with sad consequences in this investigation. Today in recovering and managing the COVID-19 Pandemic of 2020 we move forward with new welfare ideas. It is a delight to be able to share some latest work for future research based on 44 years T1 Diabetes experience complimented by Purkinje Cell environmental welfare.
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