[不同剂量率辐照对C57Bl/6小鼠生存、死亡动力学及关键系统反应的影响特点]。

Radiobiologiia Pub Date : 1992-11-01
E I Tolstykh, V S Korytnyĭ
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引用次数: 0

摘要

比较了在LD50/30至LD99-95/30的1/4范围内,不同剂量率(70、5.5和1.5 cGy/min)的致死性剂量相同或物理剂量相等的辐照对小鼠的生物学效应。就致死性而言,同样有效的剂量在肠上皮和造血系统中引起了类似的变化。在研究的剂量率范围内,死亡率动力学与LD80-95/30剂量相同。同样有效的剂量对包括cfu在内的关键系统造成了不同程度的伤害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Characteristics of the effect of irradiation at different dose rates on survival, death kinetics and response of critical systems of the C57Bl/6 mice].

A comparison was made of the biological effect on mice of irradiation at different dose rates (70, 5.5 and 1.5 cGy/min) with equally effective, with respect to lethality, doses, or with physically equal doses within the range from 1/4 of LD50/30 to LD99-95/30. Equally effective, with respect to lethality, doses caused similar changes in the intestinal epithelium and in the haemopoietic system. The death rate kinetics was identical with doses of LD80-95/30 within the dose-rate range under study. The equally effective doses caused injuries, different in degrees, to critical systems, including CFUs.

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