卡杜纳州产前诊所孕妇的急性弓形虫病

I. Edward, G. Ibrahim, M. Kabiru, E. Ikeh
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摘要

简介:刚地弓形虫急性感染可在怀孕期间垂直传播给胎儿,可能导致先天性并发症,如流产、死胎、视力障碍、癫痫、听力障碍和神经障碍。方法:采用ELISA法对357例孕妇进行急性刚地弓形虫(IgM)筛查。结果:调查显示患病率为2.8% (IgM)。16-20岁和26-30岁阳性率最高,为3例(0.8%)。而21-25岁和31-35岁的患病率为2(0.6%)阳性。然而,36-40岁的人都是阴性的。(p > 0.05)。这在年龄组中没有任何统计学意义。北部参议院区发病率最高,为8例(2.6%),其次是中部参议院区,为2例(0.2%),南部参议院区无急性弓形虫病,差异有统计学意义(p < 0.05)。结论:因此,在怀孕期间可能有机会获得急性弓形虫感染,尽管它是可以预防的,但对母亲和新生儿有潜在的悲剧性后果。在产前门诊期间,有必要提高对弓形虫筛查的积极认识和必要的设施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute Toxoplasmosis among Pregnant Women Attending Antenatal Clinic in Kaduna State
Introduction: Acute infection of Toxoplasma gondii can be transmitted during pregnancy to the foetus vertically which may cause congenital complications like abortion, stillbirth, visual impairment, seizure, hearing impairment and neurological disorders. Methodology: A total of 357 pregnant women were screened using ELISA method for acute Toxoplasma gondii (IgM). Result: The investigation however shows a prevalence of 2.8% (IgM). Ages 16-20 and 26-30 years have the highest prevalence of 3(0.8%) positive. While ages 21-25 and 31-35 years have prevalence of 2(0.6%) positive. However ages 36-40 years are all negative. (p> 0.05).This did not show any statistical significant with the age groups. Northern Senatorial zone has the highest prevalence of 8(2.6%) followed by the Central Senatorial zone with 2(0.2%) while the Southern zone shows no acute Toxoplasmosis,(p <0.05) hence it shows statistical significant. Women in their second trimesters have the highest prevalence of 7(2.0%) followed by first trimesters with prevalence of 2(0.6%) and third trimester with prevalence of 1(0.2%) positive, however it is not statistical significant (p > 0.05). Conclusion: Therefore the chance of acquiring acute infection of T. gondii is possible during pregnancy and would have potential tragic outcomes for the mother and new-born despite the fact that it can be prevented. The need for aggressive awareness and necessary facilities available for screening of T. gondii during antenatal clinic is necessary.
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