基于EGSnrc蒙特卡罗模拟的MLC叶片位置对剂量分布不准确对VMAT给药技术的影响

I. G. E. Dirgayussa, S. Yani, D. Pratama, M. F. Rhani, R. Soh, F. Haryanto
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引用次数: 1

摘要

利用蒙特卡罗仿真方法对VMAT投放技术进行了仿真,研究了MLC叶片位置规划与实际位置不准确对MLC叶片位置的影响。本研究旨在比较这两个参数之间的剂量分布。一般来说,这些研究分为两个阶段,头部直线加速器的调试和VMAT交付技术的仿真。在调试阶段,对6 × 6 cm2、10 × 10 cm2和20 × 20 cm2三种场型的PDD和剂量分布进行了蒙特卡罗模拟,并通过实验数据进行了验证。调试结果表明,仿真结果与实验结果吻合较好。在所有场尺寸下,6.4 MeV初始入射电子的平均偏差小于5%。在VMAT发射技术仿真阶段,利用自制的MATLAB程序对DynaLog文件进行分析,生成DOSXYZnrc的输入文件。分析某点取样时的一维剂量分布,以确定圆柱形丙烯酸体中剂量分布的差异。对数据文件进行动态分析表明,叶片误差小于1 mm的位置占叶片总位置的97.1%,没有叶片误差大于2 mm的位置。在等中心处发现剂量分布误差小于2%。本研究表明,由于MLC叶片位置误差小于1%,剂量分布没有显著误差。蒙特卡罗模拟采用247亿个粒子的相空间历史文件进行,蒙特卡罗计算的标准差为31.66%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Inaccuracy of MLC Leaf Position against Dose Distribution on VMAT Delivery Technique using EGSnrc Monte Carlo Simulation
A Monte Carlo simulation on VMAT delivery technique has implemented to investigate the effect of inaccuracy of MLC leaf position between the plan and the actual of MLC leaf position. The study aim to compare the dose distributions between these two parameters. In general, these studies divided into two stages, commissioning of head Linac and simulation of the VMAT delivery technique. At the commissioning stage, Monte Carlo simulation on PDD and dose profile for field size 6 × 6 cm2, 10 × 10 cm2 and 20 × 20 cm2 was validating by experimental data. Commissioning results showed a good agreement between the simulation and experimental data. The 6.4 MeV initial incident electrons were used with an average deviation less than 5% for all field size. In the VMAT delivery technique simulation stage, an analysis of DynaLog file using homemade MATLAB program is used and generated the input files for DOSXYZnrc. One dimension of dose profile analyzed at some point sampling to determine differences in the dose distribution in the cylinder acrylic phantom. DynaLog analysis on the data file showed that the leaf error position is less than 1 mm is 97.1% of the total leaf position and no leaf error position is more than 2 mm. The doses distribution error was discovered less than 2% at isocenter. This study showed there is no significant error on doses distribution due to <1% inaccuracy of MLC leaf position. The Monte Carlo simulation was done using 24.7 billion particles of the phase space history file with a standard deviation of Monte Carlo calculations by 31.66%.
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