{"title":"揭示信号转导通路的意义:癌症发展和进展的关键参与者","authors":"Emad Fadhal","doi":"10.52793/jctr.2023.3(1)-28","DOIUrl":null,"url":null,"abstract":"Signal transduction pathways play a central role in cancer development and progression by regulating various cellular processes. Dysregulation of these signaling pathways is common in cancer cells and contributes to their uncontrolled growth and survival. Targeting these aberrant signaling pathways has therefore emerged as a promising strategy to prevent cancer cell proliferation and promote therapeutic outcomes. This study highlights the critical role of signaling pathway activation and regulation in cancer biology. Furthermore, our results identified oncogenes such as PIK3CA, EGFR, AKT1, MAP2K1, AR, JAK2","PeriodicalId":325896,"journal":{"name":"Journal of Cancer Therapy and Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"\\\" Unraveling The Significance Of Signal Transduction Pathways: Key Players In Cancer Development And Progression \\\"\",\"authors\":\"Emad Fadhal\",\"doi\":\"10.52793/jctr.2023.3(1)-28\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Signal transduction pathways play a central role in cancer development and progression by regulating various cellular processes. Dysregulation of these signaling pathways is common in cancer cells and contributes to their uncontrolled growth and survival. Targeting these aberrant signaling pathways has therefore emerged as a promising strategy to prevent cancer cell proliferation and promote therapeutic outcomes. This study highlights the critical role of signaling pathway activation and regulation in cancer biology. Furthermore, our results identified oncogenes such as PIK3CA, EGFR, AKT1, MAP2K1, AR, JAK2\",\"PeriodicalId\":325896,\"journal\":{\"name\":\"Journal of Cancer Therapy and Research\",\"volume\":\"37 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cancer Therapy and Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52793/jctr.2023.3(1)-28\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cancer Therapy and Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52793/jctr.2023.3(1)-28","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
" Unraveling The Significance Of Signal Transduction Pathways: Key Players In Cancer Development And Progression "
Signal transduction pathways play a central role in cancer development and progression by regulating various cellular processes. Dysregulation of these signaling pathways is common in cancer cells and contributes to their uncontrolled growth and survival. Targeting these aberrant signaling pathways has therefore emerged as a promising strategy to prevent cancer cell proliferation and promote therapeutic outcomes. This study highlights the critical role of signaling pathway activation and regulation in cancer biology. Furthermore, our results identified oncogenes such as PIK3CA, EGFR, AKT1, MAP2K1, AR, JAK2