不完全早期妊娠流产的药物与手术治疗

Aseel Mosa
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摘要

目的:评价米索前列醇与外科手术治疗不完全流产的疗效和风险。方法:前瞻性比较研究纳入208例胎龄在5 ~ 12周的不完全流产妇女,随机分为两组,第一组给予600微克米索前列醇单次口服,第二组进行手术扩张引流。主要结果是治疗成功,所有妇女都书面同意参与试验。结果:米索前列醇组与手术组治疗后子宫内膜厚度(10.5±2.65)比较,差异无统计学意义。P值为0.251。无统计学意义,治疗失败(11比。6,其中P值为0.071,无统计学意义),失血量大于500cc者(1比。3例,P值为0.482,无显著性意义);6,其中值为0.064。治疗的副作用在被研究的女性中没有统计学上的显著差异(3例出现发烧)。1, IUS在0和。1例发生呕吐,1例发生呕吐。3在医疗方面。(P值> 0.05),但腹泻在米索前列醇治疗的女性中更为常见。分别为0,其中值< 0.001)。结论:药物治疗对不完全流产有效,可接受,费用低于手术治疗。关键词:怀孕。米索前列醇。纳西里耶的堕胎
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Medical Versus Surgical Treatment of Incomplete First Trimestric Abortion
Objective: to assess efficacy and risks of medical treatment of incomplete abortion using misoprostol versus surgical procedures. Methods: A prospective comparative study included 208 women with incomplete abortion with gestational age between 5 th and 12 th week randomized equally to two groups Group I received 600 micro gram misoprostol as single oral dose and Group II underwent surgical dilatation and evacuation. Primary outcome was successful treatment all women give a written acceptance of being involved in the trial. Results: There was no statistically significant difference between Misoprostol and surgical groups regarding endometrial thickness evaluated after treatment (10.5±2.65 versus. 9.3±1.97 respectively, where P value 0.251Non significant , treatment failure (11 versus. 6 respectively, where P value 0.071 Non significant), those with blood loss more than 500 cc ( 1 versus. 3 respectively, where P value 0.482 Non significant ) and those who needed recurrettage ((11 versus. 6 respectively, where value 0.064 Non significant). Side effects of treatment showed no statistically significant difference between the studied women (fever occurred in 3 versus. 1, IUS in 0 versus. 1 and vomiting occurred in 1 versus. 3 in medical versus. surgical women respectively ,where P value > 0.05) except diarrhea which was much more common in women under Misoprostol treatment (28 versus. 0 respectively, where value < 0.001). Conclusion: Medical treatment is effective and acceptable and less costly than surgical treatment in women with incomplete abortion. Keyward : Pregnancy. Misoprostol . Abortion in Nassiriyah
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