{"title":"不完全早期妊娠流产的药物与手术治疗","authors":"Aseel Mosa","doi":"10.32792/utq/utjmed/13/1/12","DOIUrl":null,"url":null,"abstract":"Objective: to assess efficacy and risks of medical treatment of incomplete abortion using misoprostol versus surgical procedures. Methods: A prospective comparative study included 208 women with incomplete abortion with gestational age between 5 th and 12 th week randomized equally to two groups Group I received 600 micro gram misoprostol as single oral dose and Group II underwent surgical dilatation and evacuation. Primary outcome was successful treatment all women give a written acceptance of being involved in the trial. Results: There was no statistically significant difference between Misoprostol and surgical groups regarding endometrial thickness evaluated after treatment (10.5±2.65 versus. 9.3±1.97 respectively, where P value 0.251Non significant , treatment failure (11 versus. 6 respectively, where P value 0.071 Non significant), those with blood loss more than 500 cc ( 1 versus. 3 respectively, where P value 0.482 Non significant ) and those who needed recurrettage ((11 versus. 6 respectively, where value 0.064 Non significant). Side effects of treatment showed no statistically significant difference between the studied women (fever occurred in 3 versus. 1, IUS in 0 versus. 1 and vomiting occurred in 1 versus. 3 in medical versus. surgical women respectively ,where P value > 0.05) except diarrhea which was much more common in women under Misoprostol treatment (28 versus. 0 respectively, where value < 0.001). Conclusion: Medical treatment is effective and acceptable and less costly than surgical treatment in women with incomplete abortion. Keyward : Pregnancy. Misoprostol . Abortion in Nassiriyah","PeriodicalId":152061,"journal":{"name":"University of Thi-Qar Journal of Medicine","volume":"86 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Medical Versus Surgical Treatment of Incomplete First Trimestric Abortion\",\"authors\":\"Aseel Mosa\",\"doi\":\"10.32792/utq/utjmed/13/1/12\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: to assess efficacy and risks of medical treatment of incomplete abortion using misoprostol versus surgical procedures. Methods: A prospective comparative study included 208 women with incomplete abortion with gestational age between 5 th and 12 th week randomized equally to two groups Group I received 600 micro gram misoprostol as single oral dose and Group II underwent surgical dilatation and evacuation. Primary outcome was successful treatment all women give a written acceptance of being involved in the trial. Results: There was no statistically significant difference between Misoprostol and surgical groups regarding endometrial thickness evaluated after treatment (10.5±2.65 versus. 9.3±1.97 respectively, where P value 0.251Non significant , treatment failure (11 versus. 6 respectively, where P value 0.071 Non significant), those with blood loss more than 500 cc ( 1 versus. 3 respectively, where P value 0.482 Non significant ) and those who needed recurrettage ((11 versus. 6 respectively, where value 0.064 Non significant). Side effects of treatment showed no statistically significant difference between the studied women (fever occurred in 3 versus. 1, IUS in 0 versus. 1 and vomiting occurred in 1 versus. 3 in medical versus. surgical women respectively ,where P value > 0.05) except diarrhea which was much more common in women under Misoprostol treatment (28 versus. 0 respectively, where value < 0.001). Conclusion: Medical treatment is effective and acceptable and less costly than surgical treatment in women with incomplete abortion. Keyward : Pregnancy. Misoprostol . Abortion in Nassiriyah\",\"PeriodicalId\":152061,\"journal\":{\"name\":\"University of Thi-Qar Journal of Medicine\",\"volume\":\"86 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"University of Thi-Qar Journal of Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32792/utq/utjmed/13/1/12\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"University of Thi-Qar Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32792/utq/utjmed/13/1/12","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Medical Versus Surgical Treatment of Incomplete First Trimestric Abortion
Objective: to assess efficacy and risks of medical treatment of incomplete abortion using misoprostol versus surgical procedures. Methods: A prospective comparative study included 208 women with incomplete abortion with gestational age between 5 th and 12 th week randomized equally to two groups Group I received 600 micro gram misoprostol as single oral dose and Group II underwent surgical dilatation and evacuation. Primary outcome was successful treatment all women give a written acceptance of being involved in the trial. Results: There was no statistically significant difference between Misoprostol and surgical groups regarding endometrial thickness evaluated after treatment (10.5±2.65 versus. 9.3±1.97 respectively, where P value 0.251Non significant , treatment failure (11 versus. 6 respectively, where P value 0.071 Non significant), those with blood loss more than 500 cc ( 1 versus. 3 respectively, where P value 0.482 Non significant ) and those who needed recurrettage ((11 versus. 6 respectively, where value 0.064 Non significant). Side effects of treatment showed no statistically significant difference between the studied women (fever occurred in 3 versus. 1, IUS in 0 versus. 1 and vomiting occurred in 1 versus. 3 in medical versus. surgical women respectively ,where P value > 0.05) except diarrhea which was much more common in women under Misoprostol treatment (28 versus. 0 respectively, where value < 0.001). Conclusion: Medical treatment is effective and acceptable and less costly than surgical treatment in women with incomplete abortion. Keyward : Pregnancy. Misoprostol . Abortion in Nassiriyah